Associations of childhood trauma with hypothalamic-pituitary-adrenal function in borderline personality disorder and major depression.

  • Carvalho Fernando Silvia
  • Thomas Beblo
  • Nicole Schlosser
  • Kirsten Terfehr
  • Christian Otte
  • Bernd Löwe
  • Oliver Tobias Wolf
  • Carsten Spitzer
  • Martin Driessen
  • Katja Wingenfeld

Abstract

Alterations of the hypothalamus-pituitary-adrenal (HPA) axis are hallmarks in major depressive disorder (MDD) and there is some evidence about similar patterns in borderline personality disorder (BPD). This study examines HPA axis abnormalities with respect to clinical characteristics in both BPD (n=24) and MDD patients (n=33) as well as in healthy control participants (n=41).

Bibliographical data

Original languageEnglish
Article number10
ISSN0306-4530
Publication statusPublished - 2012
pubmed 22444624