Arterial mechanical properties after replacement or reconstruction of the aortic root
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Arterial mechanical properties after replacement or reconstruction of the aortic root. / Mortensen, Kai; Aydin, Muhammet Ali; Bernhardt, Alexander; Appenzeller, Verena; Robinson, Peter N; Berger, Jürgen; Reichenspurner, Hermann; von Kodolitsch, Yskert.
In: World J Cardiovasc Dis, Vol. 2, 2012, p. 8-13.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Arterial mechanical properties after replacement or reconstruction of the aortic root
AU - Mortensen, Kai
AU - Aydin, Muhammet Ali
AU - Bernhardt, Alexander
AU - Appenzeller, Verena
AU - Robinson, Peter N
AU - Berger, Jürgen
AU - Reichenspurner, Hermann
AU - von Kodolitsch, Yskert
PY - 2012
Y1 - 2012
N2 - Background: Alteration of arterial mechanical prop- erties has adverse effects on cardiovascular disease in Marfan syndrome. Design: We compared central pulse pressure, augmentation index adjusted to a heart rate of 75 beats per minute (AIx@HR75) and pulse wave velocity in 25 Marfan patients who had undergone an aortic valve-sparing reimplantation ope- ration, in 15 Marfan patients after composite valve grafting operation, and in 40 age and sex-matched Marfan patients who had not undergone surgery. Re- sults: Central pulse pressure, AIx@HR75 and pulse wave velocity were similar across all three patient groups. Exclusively AIx@HR75 was higher with con- duit operations than in persons without any surgery (P = 0.03). Multivariate linear regression analysis docu- mented association of AIx@HR75 with body height (P < 0.001) and with a history of aortic valve-sparing reimplantation operation (P < 0.001) or with a com- posite valve grafting operation (P = 0.006). Conclu- sions: Arterial mechanical properties are only mildly altered by surgery of the aortic root without difference between the reimplantation and conduit operation.
AB - Background: Alteration of arterial mechanical prop- erties has adverse effects on cardiovascular disease in Marfan syndrome. Design: We compared central pulse pressure, augmentation index adjusted to a heart rate of 75 beats per minute (AIx@HR75) and pulse wave velocity in 25 Marfan patients who had undergone an aortic valve-sparing reimplantation ope- ration, in 15 Marfan patients after composite valve grafting operation, and in 40 age and sex-matched Marfan patients who had not undergone surgery. Re- sults: Central pulse pressure, AIx@HR75 and pulse wave velocity were similar across all three patient groups. Exclusively AIx@HR75 was higher with con- duit operations than in persons without any surgery (P = 0.03). Multivariate linear regression analysis docu- mented association of AIx@HR75 with body height (P < 0.001) and with a history of aortic valve-sparing reimplantation operation (P < 0.001) or with a com- posite valve grafting operation (P = 0.006). Conclu- sions: Arterial mechanical properties are only mildly altered by surgery of the aortic root without difference between the reimplantation and conduit operation.
UR - http://www.scirp.org/journal/PaperInformation.aspx?PaperID=16599
U2 - 10.4236/wjcd.2012.21002
DO - 10.4236/wjcd.2012.21002
M3 - SCORING: Journal article
VL - 2
SP - 8
EP - 13
JO - World J Cardiovasc Dis
JF - World J Cardiovasc Dis
SN - 2164-5329
ER -