Application of the SCAI classification in a cohort of patients with cardiogenic shock
Standard
Application of the SCAI classification in a cohort of patients with cardiogenic shock. / Schrage, Benedikt; Dabboura, Salim; Yan, Isabell; Hilal, Rafel; Neumann, Johannes T; Sörensen, Nils A; Goßling, Alina; Becher, Peter Moritz; Grahn, Hanno; Wagner, Tobias; Seiffert, Moritz; Kluge, Stefan; Reichenspurner, Hermann; Blankenberg, Stefan; Westermann, Dirk.
In: CATHETER CARDIO INTE, Vol. 96, No. 3, 01.09.2020, p. E213-E219.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Application of the SCAI classification in a cohort of patients with cardiogenic shock
AU - Schrage, Benedikt
AU - Dabboura, Salim
AU - Yan, Isabell
AU - Hilal, Rafel
AU - Neumann, Johannes T
AU - Sörensen, Nils A
AU - Goßling, Alina
AU - Becher, Peter Moritz
AU - Grahn, Hanno
AU - Wagner, Tobias
AU - Seiffert, Moritz
AU - Kluge, Stefan
AU - Reichenspurner, Hermann
AU - Blankenberg, Stefan
AU - Westermann, Dirk
N1 - © 2020 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals, Inc.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - BACKGROUND: The Society of Cardiovascular Angiography and Interventions (SCAI) have recently proposed a new classification of cardiogenic shock (CS) dividing patients into five subgroups.OBJECTIVE: Aim of this study was to apply the SCAI classification to a cohort of patients presenting with CS and to evaluate its ability to predict 30-day survival.METHODS: SCAI CS subgroups were interpreted based on the recent consensus statement and then applied to N = 1,007 consecutive patients presenting with CS or large myocardial infarction (MI) between October 2009 and October 2017. The association between SCAI classification and 30-day all-cause mortality was assessed by logistic regression analysis.RESULTS: Mean age in the study cohort was 67 (±15) years, 72% were male. Mean lactate at baseline was 6.05 (±5.13) mmol/l and 51% of the patients had prior cardiac arrest. Overall survival probability was 50.6% (95% confidence interval [CI] 47.5-54.0%). In view of the SCAI classification, the survival probability was 96.4% (95% CI 93.7-99.0%) in class A, 66.1% (95% CI 50.2-87.1%) in class B, 46.1% (95% CI 40.6-52.4%) in class C, 33.1% (95% CI 26.6-41.1%) in class D, and 22.6% (95% CI 17.1-30.0%) in class E. Higher SCAI classification was significantly associated with lower 30-day survival (p < .01).CONCLUSION: In this large clinical cohort, the SCAI classification was significantly associated with 30-day survival. This finding supports the rationale of the SCAI CS classification and calls for a validation in a prospective trial.
AB - BACKGROUND: The Society of Cardiovascular Angiography and Interventions (SCAI) have recently proposed a new classification of cardiogenic shock (CS) dividing patients into five subgroups.OBJECTIVE: Aim of this study was to apply the SCAI classification to a cohort of patients presenting with CS and to evaluate its ability to predict 30-day survival.METHODS: SCAI CS subgroups were interpreted based on the recent consensus statement and then applied to N = 1,007 consecutive patients presenting with CS or large myocardial infarction (MI) between October 2009 and October 2017. The association between SCAI classification and 30-day all-cause mortality was assessed by logistic regression analysis.RESULTS: Mean age in the study cohort was 67 (±15) years, 72% were male. Mean lactate at baseline was 6.05 (±5.13) mmol/l and 51% of the patients had prior cardiac arrest. Overall survival probability was 50.6% (95% confidence interval [CI] 47.5-54.0%). In view of the SCAI classification, the survival probability was 96.4% (95% CI 93.7-99.0%) in class A, 66.1% (95% CI 50.2-87.1%) in class B, 46.1% (95% CI 40.6-52.4%) in class C, 33.1% (95% CI 26.6-41.1%) in class D, and 22.6% (95% CI 17.1-30.0%) in class E. Higher SCAI classification was significantly associated with lower 30-day survival (p < .01).CONCLUSION: In this large clinical cohort, the SCAI classification was significantly associated with 30-day survival. This finding supports the rationale of the SCAI CS classification and calls for a validation in a prospective trial.
U2 - 10.1002/ccd.28707
DO - 10.1002/ccd.28707
M3 - SCORING: Journal article
C2 - 31925996
VL - 96
SP - E213-E219
JO - CATHETER CARDIO INTE
JF - CATHETER CARDIO INTE
SN - 1522-1946
IS - 3
ER -