(68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer
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(68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer : Abdom Imaging. / Eiber, M.; Nekolla, S. G.; Maurer, T.; Weirich, G.; Wester, H. J.; Schwaiger, M.
In: ABDOM IMAGING, Vol. 40, No. 6, 2015, p. 1769-1771.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research
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TY - JOUR
T1 - (68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer
T2 - Abdom Imaging
AU - Eiber, M.
AU - Nekolla, S. G.
AU - Maurer, T.
AU - Weirich, G.
AU - Wester, H. J.
AU - Schwaiger, M.
N1 - 1432-0509 Eiber, Matthias Nekolla, Stephan G Maurer, Tobias Weirich, Gregor Wester, Hans-Jurgen Schwaiger, Markus Case Reports Journal Article United States Abdom Imaging. 2015 Aug;40(6):1769-71. doi: 10.1007/s00261-014-0301-z.
PY - 2015
Y1 - 2015
N2 - Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a (68)Gallium-labeled ligand of the prostate-specific membrane antigen ((68)Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68 Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric (68)Ga-PSMA PET/MR by combining molecular and structural information.
AB - Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a (68)Gallium-labeled ligand of the prostate-specific membrane antigen ((68)Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68 Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric (68)Ga-PSMA PET/MR by combining molecular and structural information.
KW - Aged Antigens, Surface Edetic Acid/analogs & derivatives Gallium Radioisotopes Glutamate Carboxypeptidase II Humans Magnetic Resonance Imaging Male Multimodal Imaging Neoplasm Staging/methods Oligopeptides Positron-Emission Tomography Preoperative Care Pr
U2 - 10.1007/s00261-014-0301-z
DO - 10.1007/s00261-014-0301-z
M3 - SCORING: Journal article
VL - 40
SP - 1769
EP - 1771
JO - ABDOM IMAGING
JF - ABDOM IMAGING
SN - 0942-8925
IS - 6
ER -