Prof. Dr. ID: 65683

Boris Fehse

graph of relations

Publications

  1. 5-azacytidine promotes an inhibitory T-cell phenotype and impairs immune mediated antileukemic activity

    Stübig, T., Badbaran, A., Luetkens, T., Hildebrandt, Y., Atanackovic, D., Binder, T. M. C., Fehse, B. & Kröger, N-M., 13.03.2014, In: MEDIAT INFLAMM. 2014, p. 418292

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  2. Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance.

    Bennour, E., Ferrand, C., Rémy-Martin, J-P., Certoux, J-M., Gorke, S., Qasim, W., Gaspar, H. B., Baumert, T., Duperrier, A., Deschamps, M., Fehse, B., Tiberghien, P. & Robinet, E., 2008, In: HUM GENE THER. 19, 7, p. 699-709 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells

    Michaelis, M., Rothweiler, F., Barth, S., Cinatl, J., van Rikxoort, M., Löschmann, N., Voges, Y., Breitling, R., von Deimling, A., Rödel, F., Riecken, K., Fehse, B., Mack, E., Stiewe, T., Doerr, H. W., Speidel, D., Cinatl, J. & Riecken, K., 01.01.2011, In: CELL DEATH DIS. 2, p. e243

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. A High-Throughput HIV-1 Drug Screening Platform, Based on Lentiviral Vectors and Compatible with Biosafety Level-1

    Ellinger, B., Pohlmann, D., Woens, J., Jäkel, F. M., Reinshagen, J., Stocking, C., Prassolov, V. S., Fehse, B. & Riecken, K., 25.05.2020, In: VIRUSES-BASEL. 12, 5

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Allogeneic stem-cell transplantation in patients with refractory acute leukemia: a long-term follow-up.

    Oyekunle, A. A., Kröger, N., Zabelina, T., Ayuketang Ayuk, F., Schieder, H., Renges, H., Fehse, N., Waschke, O., Fehse, B., Kabisch, H. & Zander, A. R., 2006, In: BONE MARROW TRANSPL. 37, 1, p. 45-50 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes

    Labenski, V., Suerth, J. D., Barczak, E., Heckl, D., Levy, C., Bernadin, O., Charpentier, E., Williams, D. A., Fehse, B., Verhoeyen, E. & Schambach, A., 26.04.2016, In: BIOMATERIALS. 97, p. 97-109 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis

    Weber, K., Bartsch, U., Stocking, C. & Fehse, B., 2008, In: MOL THER. 16, 4, p. 698-706 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Analysis of progenitor cell mobilization and erythropoietin plasma levels in patients with acute myocardial infarction

    Krause, K., Fehse, B., Jaquet, K., Lange, C., Kyriazis, K., Boczor, S., Zander, A. & Kuck, K-H., 01.01.2005, In: EXP CLIN CARDIOL. 10, 2, p. 104-7 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN) vectors and multi-colour analyses

    Prokofjeva, M. M., Riecken, K., Spirin, P. V., Yanvarév, D. V., Düsedau, A., Ellinger, B., Fehse, B., Stocking, C. & Prassolov, V. S., 01.01.2013, In: AIDS research and therapy. 10, 1, p. 1

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. A novel 'sort-suicide' fusion gene vector for T cell manipulation

    Fehse, B., Kustikova, O. S., Li, Z., Wahlers, A., Bohn, W., Beyer, W. R., Chalmers, D., Tiberghien, P., Kühlcke, K., Zander, A. R. & Baum, C., 12.2002, In: GENE THER. 9, 23, p. 1633-1638 6 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  11. Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells.

    Rothweiler, F., Michaelis, M., Brauer, P., Otte, J., Riecken, K., Fehse, B., Doerr, H. W., Wiese, M., Kreuter, J., Al-Abed, Y., Nicoletti, F. & Cinatl, J., 2010, In: NEOPLASIA. 12, 12, p. 1023-1030 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Antithymocyte globulin induces ex vivo and in vivo depletion of myeloid and plasmacytoid dendritic cells

    Fang, L., Fehse, B., Engel, M., Zander, A. & Kröger, N., 15.02.2005, In: TRANSPLANTATION. 79, 3, p. 369-371 3 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  13. Anti-thymocyte globulin overcomes the negative impact of HLA mismatching in transplantation from unrelated donors.

    Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Panse, J., Wolschke, C., Eiermann, T., Binder, T., Fehse, B., Erttmann, R., Kabisch, H., Bacher, U., Kröger, N. & Zander, A. R., 2008, In: EXP HEMATOL. 36, 8, p. 1047-1054 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Anwendung des Genome Editing in der somatischen Gentherapie: Eine Einführung

    Fehse, B. & Abramowski-Mock, U., 03.2021, Anwendung des Genome Editing in der somatischen Gentherapie. 1 ed. Wiesbaden: Springer, 48 p. (essentials).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesTransfer

  15. Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma.

    Kröger, N-M., Schwerdtfeger, R., Kiehl, M., Sayer, H. G., Renges, H-H., Zabelina, T., Fehse, B., Tögel, F., Wittkowsky, G., Kuse, R. & Zander, A., 2002, In: BLOOD. 100, 3, p. 755-760 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Automated production of CCR5-negative CD4+-T cells in a GMP-compatible, clinical scale for treatment of HIV-positive patients

    Schwarze, L. I., Sonntag, T., Wild, S., Schmitz, S., Uhde, A. & Fehse, B., 09.2021, In: GENE THER. 28, 9, p. 572-587 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Axicabtagene ciloleucel in vivo expansion and treatment outcome in aggressive B-cell lymphoma in a real-world setting

    Ayuk, F. A., Berger, C., Badbaran, A., Zabelina, T., Sonntag, T., Riecken, K., Geffken, M., Wichmann, D., Frenzel, C., Thayssen, G., Zeschke, S., Kröger, N. & Fehse, B., 08.06.2021, In: BLOOD ADV. 5, 11, p. 2523-2527 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

    Ben Batalla, I., Schultze, A., Wroblewski, M., Erdmann, R., Heuser, M., Waizenegger, J. S., Riecken, K., Binder, M., Schewe, D., Sawall, S., Witzke, V., Cubas Cordova, M., Janning, M., Wellbrock, J., Fehse, B., Hagel, C., Krauter, J., Ganser, A., Lorens, J. B., Fiedler, W., Carmeliet, P., Pantel, K., Bokemeyer, C. & Loges, S., 03.10.2013, In: BLOOD. 122, 14, p. 2443-52 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism

    Oehler, N., Volz, T., Bhadra, O. D., Kah, J., Allweiss, L., Giersch, K., Bierwolf, J., Riecken, K., Pollok, J. M., Lohse, A. W., Fehse, B., Petersen, J., Urban, S., Lütgehetmann, M., Heeren, J. & Dandri, M., 08.04.2014, In: HEPATOLOGY.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Bone marrow mesenchymal stromal cells remain of recipient origin after allogeneic SCT and do not harbor the JAK2V617F mutation in patients with myelofibrosis.

    Bacher, U., Asenova, S., Badbaran, A., Zander, A. R., Alchalby, H., Fehse, B., Kröger, N., Lange, C. & Ayuketang Ayuk, F., 2009, In: CLIN EXP MED.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling

    Tintelnot, J., Metz, S., Trentmann, M., Oberle, A., von Wenserski, L., Schultheiß, C., Braig, F., Kriegs, M., Fehse, B., Riecken, K., Bokemeyer, C., Stein, A. & Binder, M., 2019, In: FRONT ONCOL. 9, p. 1559

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Cancer Suicide Gene Therapy with TK.007

    Hossain, J. A., Riecken, K., Miletic, H. & Fehse, B., 2019, In: Methods Mol Biol. 1895, p. 11-26 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect.

    Preuß, E., Muik, A., Riecken, K., Otte, J., von Laer, D. & Fehse, B., 2011, In: J MOL MED. 89, 11, p. 1113-1124 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Cancer-testis antigen MAGE-C2/CT10 induces spontaneous CD4+ and CD8+ T-cell responses in multiple myeloma patients

    Reinhard, H., Yousef, S., Luetkens, T., Fehse, B., Berdien, B., Kröger, N. & Atanackovic, D., 01.01.2014, In: BLOOD CANCER J. 4, p. e212

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. CAR-HEMATOTOX: A model for CAR T-cell related hematological toxicity in relapsed/refractory large B-cell lymphoma

    Rejeski, K., Perez Perez, A., Sesques, P., Hoster, E., Berger, C. S., Jentzsch, L., Mougiakakos, D., Frölich, L., Ackermann, J., Buecklein, V., Blumenberg, V., Schmidt, C., Jallades, L., Fehse, B., Faul, C., Karschnia, P., Weigert, O., Dreyling, M., Locke, F. L., von Bergwelt-Baildon, M., Mackensen, A., Bethge, W. A., Ayuk, F., Bachy, E., Salles, G. A., Jain, M. D. & Subklewe, M., 16.12.2021, In: BLOOD. 138, 24, p. 2499-2513 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. CARs come to AID

    Ayuk, F. & Fehse, B., 03.04.2024, In: MOL THER. 32, 4, p. 861-862 2 p.

    Research output: SCORING: Contribution to journalEditorialResearch

  27. CD133 marks a stem cell population that drives human Primary Myelofibrosis

    Triviai, I., Stübig, T., Niebuhr, B., Hussein, K., Tsiftsoglou, A., Fehse, B., Stocking, C. & Kröger, N., 27.02.2015, In: HAEMATOLOGICA. 100, 6, p. 768-79

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. CD19-targeted chimeric antigen receptor T cell therapy in two patients with multiple sclerosis

    Fischbach, F., Richter, J., Pfeffer, L. K., Fehse, B., Berger, S. C., Reinhardt, S., Kuhle, J., Badbaran, A., Rathje, K., Gagelmann, N., Borie, D., Seibel, J., Ayuk, F., Friese, M. A., Heesen, C. & Kröger, N., 14.06.2024, In: MED-CAMBRIDGE. 5, 6, p. 550-558.e2

    Research output: SCORING: Contribution to journalCase reportResearchpeer-review

  29. CD34 modulates the trafficking behavior of hematopoietic cells in vivo.

    Lange, C., Li, Z., Fang, L., Baum, C. & Fehse, B., 2007, In: STEM CELLS DEV. 16, 2, p. 297-304 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. CD34(+)-selected stem cell boost for delayed or insufficient engraftment after allogeneic stem cell transplantation.

    Oyekunle, A., Koehl, U., Schieder, H., Ayuketang Ayuk, F., Renges, H., Fehse, N., Zabelina, T., Fehse, B., Klingebiel, T., Sputtek, A., Zander, A. R. & Kröger, N., 2006, In: CYTOTHERAPY. 8, 4, p. 375-380 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. CD34 splice variant: an attractive marker for selection of gene-modified cells

    Fehse, B., Richters, A., Putimtseva-Scharf, K., Klump, H., Li, Z., Ostertag, W., Zander, A. R. & Baum, C., 05.2000, In: MOL THER. 1, 5 Pt 1, p. 448-456 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. CD45-Directed CAR-T Cells with CD45 Knockout Efficiently Kill Myeloid Leukemia and Lymphoma Cells In Vitro Even after Extended Culture

    Harfmann, M., Schröder, T., Głów, D., Jung, M., Uhde, A., Kröger, N., Horn, S., Riecken, K., Fehse, B. & Ayuk, F. A., 12.01.2024, In: CANCERS. 16, 2, 334.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation.

    Atanackovic, D., Cao, Y., Luetkens, T., Panse, J., Faltz, C., Arfsten, J., Bartels, K., Wolschke, C., Eiermann, T., Zander, A. R., Fehse, B., Bokemeyer, C. & Kröger, N., 2008, In: HAEMATOLOGICA. 93, 3, p. 423-430 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Cell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertag (1937-2010).

    Stocking, C., Grez, M., Fehse, B., von Laer, D., Itoh, K., Prassolov, V., Nowock, J., Kühlcke, K., Just, U., Schröder, T., Klump, H., Schiedlmeier, B., Grassman, E., Meyer, J., Li, Z., Schambach, A., Modlich, U., Kustikova, O., Galla, M., Jürgen, B., Zander, A. R. & Baum, C., 2010, In: HUM GENE THER. 21, 11, p. 1501-1503 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma

    Roh, V., Abramowski, P., Hiou-Feige, A., Cornils, K., Rivals, J-P., Zougman, A., Aranyossy, T., Thielecke, L., Truan, Z., Mermod, M., Monnier, Y., Prassolov, V., Glauche, I., Nowrouzi, A., Abdollahi, A., Fehse, B., Simon, C. & Tolstonog, G. V., 20.11.2018, In: CELL REP. 25, 8, p. 2208-2222.e7

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Cellular Therapy with Engineered T Cells, Efficacy and Side Effects

    Bondanza, A., Bonini, C., Fehse, B. & Hudecek, M., 2019, The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies: The EBMT Handbook. Carreras, E., Dufour, C., Mohty, M. & Kröger, N. (eds.). 1 ed. Springer Nature Switzerland AG, p. 449-456 8 p.

    Research output: SCORING: Contribution to book/anthologyChapterResearch

  37. Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-KPolymorphism

    Braig, F., Kriegs, M., Voigtlaender, M., Habel, B., Grob, T., Biskup, K., Blanchard, V., Sack, M., Thalhammer, A., Ben Batalla, I., Braren, I., Laban, S., Danielczyk, A., Goletz, S., Jakubowicz, E., Märkl, B., Trepel, M., Knecht, R., Riecken, K., Fehse, B., Loges, S., Bokemeyer, C. & Binder, M., 01.03.2017, In: CANCER RES. 77, 5, p. 1188-1199 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Chancen und Risiken der CAR-T-Zell-Therapie

    Ayuk, F. A., Fehse, B., Berger, S. C., Riecken, K. & Kroger, N., 10.2019, In: Hamb Ärztebl. 73, 10, p. 30-32

    Research output: SCORING: Contribution to journalSCORING: Review articleEducation

  39. Chance or necessity? Insertional mutagenesis in gene therapy and its consequences

    Baum, C., von Kalle, C., Staal, F. J. T., Li, Z., Fehse, B., Schmidt, M., Weerkamp, F., Karlsson, S., Wagemaker, G. & Williams, D. A., 01.2004, In: MOL THER. 9, 1, p. 5-13 9 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  40. Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal

    Grochowska, K. M., Sperveslage, M., Raman, R., Failla, A. V., Głów, D., Schulze, C., Laprell, L., Fehse, B. & Kreutz, M. R., 29.08.2023, In: CELL REP. 42, 8, p. 112998

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Chimeric autoantibody receptor cell therapy for the treatment of membranous nephropathy: The authors reply

    Fehse, B. & Tomas, N. M., 06.2024, In: KIDNEY INT. 105, 6, p. 1320-1321 2 p.

    Research output: SCORING: Contribution to journalLetterResearch

  42. Chimerism studies with quantitative real-time PCR in stem cell recipients with acute myeloid leukemia.

    Wiedemann, B., Klyuchnikov, E., Kröger, N., Zabelina, T., Stahl, T., Zeschke, S., Badbaran, A., Ayuketang Ayuk, F., Alchalby, H., Wolschke, C., Bokemeyer, C., Fehse, B., Zander, A. R. & Bacher, U., 2010, In: EXP HEMATOL. 38, 12, p. 1261-1271 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Clinical application of a retroviral gene transfer protocol based on centrifugation-mediated vector preloading.

    Fehse, B., 2008, In: HUM GENE THER. 19, 6, p. 655-658 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion

    Cornils, K., Thielecke, L., Winkelmann, D., Aranyossy, T., Lesche, M., Dahl, A., Roeder, I., Fehse, B. & Glauche, I., 14.07.2017, In: MOL CANCER. 16, 1, p. 120

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking

    Kustikova, O., Fehse, B., Modlich, U., Yang, M., Düllmann, J., Kamino, K., von Neuhoff, N., Schlegelberger, B., Li, Z. & Baum, C., 20.05.2005, In: SCIENCE. 308, 5725, p. 1171-4 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks

    Brenière-Letuffe, D., Domke-Shibamiya, A., Hansen, A., Eschenhagen, T., Fehse, B., Riecken, K. & Stenzig, J., 18.06.2018, In: STEM CELL RES THER. 9, 1, p. 165

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Clonal Evolution after Allogeneic Hematopoietic Stem Cell Transplantation

    Christopeit, M., Badbaran, A., Alawi, M., Flach, J., Fehse, B. & Kröger, N., 07.2020, In: BIOL BLOOD MARROW TR. 26, 7, p. e167-e170

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Combined Application of RGB Marking and Mass Spectrometric Imaging Facilitates Detection of Tumor Heterogeneity

    Abramowski, P., Kraus, O., Rohn, S., Riecken, K., Fehse, B. & Schlüter, H., 03.07.2015, In: CANCER GENOM PROTEOM. 12, 4, p. 179-187 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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