Prof. Dr. ID: 65683
Boris Fehse
Publications
5-azacytidine promotes an inhibitory T-cell phenotype and impairs immune mediated antileukemic activity
Stübig, T., Badbaran, A., Luetkens, T., Hildebrandt, Y., Atanackovic, D., Binder, T. M. C., Fehse, B. & Kröger, N-M., 13.03.2014, In: MEDIAT INFLAMM. 2014, p. 418292Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance.
Bennour, E., Ferrand, C., Rémy-Martin, J-P., Certoux, J-M., Gorke, S., Qasim, W., Gaspar, H. B., Baumert, T., Duperrier, A., Deschamps, M., Fehse, B., Tiberghien, P. & Robinet, E., 2008, In: HUM GENE THER. 19, 7, p. 699-709 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Accurate In-Vivo Quantification of CD19 CAR-T Cells after Treatment with Axicabtagene Ciloleucel (Axi-Cel) and Tisagenlecleucel (Tisa-Cel) Using Digital PCR
Badbaran, A., Berger, C., Riecken, K., Kruchen, A., Geffken, M., Müller, I., Kröger, N., Ayuk, F. A. & Fehse, B., 20.07.2020, In: CANCERS. 12, 7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells
Michaelis, M., Rothweiler, F., Barth, S., Cinatl, J., van Rikxoort, M., Löschmann, N., Voges, Y., Breitling, R., von Deimling, A., Rödel, F., Riecken, K., Fehse, B., Mack, E., Stiewe, T., Doerr, H. W., Speidel, D., Cinatl, J. & Riecken, K., 01.01.2011, In: CELL DEATH DIS. 2, p. e243Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A High-Throughput HIV-1 Drug Screening Platform, Based on Lentiviral Vectors and Compatible with Biosafety Level-1
Ellinger, B., Pohlmann, D., Woens, J., Jäkel, F. M., Reinshagen, J., Stocking, C., Prassolov, V. S., Fehse, B. & Riecken, K., 25.05.2020, In: VIRUSES-BASEL. 12, 5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic stem-cell transplantation in patients with refractory acute leukemia: a long-term follow-up.
Oyekunle, A. A., Kröger, N., Zabelina, T., Ayuketang Ayuk, F., Schieder, H., Renges, H., Fehse, N., Waschke, O., Fehse, B., Kabisch, H. & Zander, A. R., 2006, In: BONE MARROW TRANSPL. 37, 1, p. 45-50 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes
Labenski, V., Suerth, J. D., Barczak, E., Heckl, D., Levy, C., Bernadin, O., Charpentier, E., Williams, D. A., Fehse, B., Verhoeyen, E. & Schambach, A., 26.04.2016, In: BIOMATERIALS. 97, p. 97-109 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis
Weber, K., Bartsch, U., Stocking, C. & Fehse, B., 2008, In: MOL THER. 16, 4, p. 698-706 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Analysis of progenitor cell mobilization and erythropoietin plasma levels in patients with acute myocardial infarction
Krause, K., Fehse, B., Jaquet, K., Lange, C., Kyriazis, K., Boczor, S., Zander, A. & Kuck, K-H., 01.01.2005, In: EXP CLIN CARDIOL. 10, 2, p. 104-7 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An antigen-specific chimeric autoantibody receptor (CAAR) NK cell strategy for the elimination of anti-PLA2R1 and anti-THSD7A antibody-secreting cells
Seifert, L., Riecken, K., Zahner, G., Hambach, J., Hagenstein, J., Dubberke, G., Huber, T. B., Koch-Nolte, F., Fehse, B. & Tomas, N. M., 04.2024, In: KIDNEY INT. 105, 4, p. 886-889 4 p.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN) vectors and multi-colour analyses
Prokofjeva, M. M., Riecken, K., Spirin, P. V., Yanvarév, D. V., Düsedau, A., Ellinger, B., Fehse, B., Stocking, C. & Prassolov, V. S., 01.01.2013, In: AIDS research and therapy. 10, 1, p. 1Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel 'sort-suicide' fusion gene vector for T cell manipulation
Fehse, B., Kustikova, O. S., Li, Z., Wahlers, A., Bohn, W., Beyer, W. R., Chalmers, D., Tiberghien, P., Kühlcke, K., Zander, A. R. & Baum, C., 12.2002, In: GENE THER. 9, 23, p. 1633-1638 6 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells.
Rothweiler, F., Michaelis, M., Brauer, P., Otte, J., Riecken, K., Fehse, B., Doerr, H. W., Wiese, M., Kreuter, J., Al-Abed, Y., Nicoletti, F. & Cinatl, J., 2010, In: NEOPLASIA. 12, 12, p. 1023-1030 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antithymocyte globulin induces ex vivo and in vivo depletion of myeloid and plasmacytoid dendritic cells
Fang, L., Fehse, B., Engel, M., Zander, A. & Kröger, N., 15.02.2005, In: TRANSPLANTATION. 79, 3, p. 369-371 3 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Anti-thymocyte globulin overcomes the negative impact of HLA mismatching in transplantation from unrelated donors.
Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Panse, J., Wolschke, C., Eiermann, T., Binder, T., Fehse, B., Erttmann, R., Kabisch, H., Bacher, U., Kröger, N. & Zander, A. R., 2008, In: EXP HEMATOL. 36, 8, p. 1047-1054 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Anwendung des Genome Editing in der somatischen Gentherapie: Eine Einführung
Fehse, B. & Abramowski-Mock, U., 03.2021, Anwendung des Genome Editing in der somatischen Gentherapie. 1 ed. Wiesbaden: Springer, 48 p. (essentials).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma.
Kröger, N-M., Schwerdtfeger, R., Kiehl, M., Sayer, H. G., Renges, H-H., Zabelina, T., Fehse, B., Tögel, F., Wittkowsky, G., Kuse, R. & Zander, A., 2002, In: BLOOD. 100, 3, p. 755-760 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Automated production of CCR5-negative CD4+-T cells in a GMP-compatible, clinical scale for treatment of HIV-positive patients
Schwarze, L. I., Sonntag, T., Wild, S., Schmitz, S., Uhde, A. & Fehse, B., 09.2021, In: GENE THER. 28, 9, p. 572-587 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Axicabtagene ciloleucel in vivo expansion and treatment outcome in aggressive B-cell lymphoma in a real-world setting
Ayuk, F. A., Berger, C., Badbaran, A., Zabelina, T., Sonntag, T., Riecken, K., Geffken, M., Wichmann, D., Frenzel, C., Thayssen, G., Zeschke, S., Kröger, N. & Fehse, B., 08.06.2021, In: BLOOD ADV. 5, 11, p. 2523-2527 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma
Ben Batalla, I., Schultze, A., Wroblewski, M., Erdmann, R., Heuser, M., Waizenegger, J. S., Riecken, K., Binder, M., Schewe, D., Sawall, S., Witzke, V., Cubas Cordova, M., Janning, M., Wellbrock, J., Fehse, B., Hagel, C., Krauter, J., Ganser, A., Lorens, J. B., Fiedler, W., Carmeliet, P., Pantel, K., Bokemeyer, C. & Loges, S., 03.10.2013, In: BLOOD. 122, 14, p. 2443-52 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
Oehler, N., Volz, T., Bhadra, O. D., Kah, J., Allweiss, L., Giersch, K., Bierwolf, J., Riecken, K., Pollok, J. M., Lohse, A. W., Fehse, B., Petersen, J., Urban, S., Lütgehetmann, M., Heeren, J. & Dandri, M., 08.04.2014, In: HEPATOLOGY.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone marrow mesenchymal stromal cells remain of recipient origin after allogeneic SCT and do not harbor the JAK2V617F mutation in patients with myelofibrosis.
Bacher, U., Asenova, S., Badbaran, A., Zander, A. R., Alchalby, H., Fehse, B., Kröger, N., Lange, C. & Ayuketang Ayuk, F., 2009, In: CLIN EXP MED.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling
Tintelnot, J., Metz, S., Trentmann, M., Oberle, A., von Wenserski, L., Schultheiß, C., Braig, F., Kriegs, M., Fehse, B., Riecken, K., Bokemeyer, C., Stein, A. & Binder, M., 2019, In: FRONT ONCOL. 9, p. 1559Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer Suicide Gene Therapy with TK.007
Hossain, J. A., Riecken, K., Miletic, H. & Fehse, B., 2019, In: Methods Mol Biol. 1895, p. 11-26 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect.
Preuß, E., Muik, A., Riecken, K., Otte, J., von Laer, D. & Fehse, B., 2011, In: J MOL MED. 89, 11, p. 1113-1124 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer-testis antigen MAGE-C2/CT10 induces spontaneous CD4+ and CD8+ T-cell responses in multiple myeloma patients
Reinhard, H., Yousef, S., Luetkens, T., Fehse, B., Berdien, B., Kröger, N. & Atanackovic, D., 01.01.2014, In: BLOOD CANCER J. 4, p. e212Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CAR-HEMATOTOX: A model for CAR T-cell related hematological toxicity in relapsed/refractory large B-cell lymphoma
Rejeski, K., Perez Perez, A., Sesques, P., Hoster, E., Berger, C. S., Jentzsch, L., Mougiakakos, D., Frölich, L., Ackermann, J., Buecklein, V., Blumenberg, V., Schmidt, C., Jallades, L., Fehse, B., Faul, C., Karschnia, P., Weigert, O., Dreyling, M., Locke, F. L., von Bergwelt-Baildon, M., Mackensen, A., Bethge, W. A., Ayuk, F., Bachy, E., Salles, G. A., Jain, M. D. & Subklewe, M., 16.12.2021, In: BLOOD. 138, 24, p. 2499-2513 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CARs come to AID
Ayuk, F. & Fehse, B., 03.04.2024, In: MOL THER. 32, 4, p. 861-862 2 p.Research output: SCORING: Contribution to journal › Editorial › Research
CD133 marks a stem cell population that drives human Primary Myelofibrosis
Triviai, I., Stübig, T., Niebuhr, B., Hussein, K., Tsiftsoglou, A., Fehse, B., Stocking, C. & Kröger, N., 27.02.2015, In: HAEMATOLOGICA. 100, 6, p. 768-79Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD19-targeted chimeric antigen receptor T cell therapy in two patients with multiple sclerosis
Fischbach, F., Richter, J., Pfeffer, L. K., Fehse, B., Berger, S. C., Reinhardt, S., Kuhle, J., Badbaran, A., Rathje, K., Gagelmann, N., Borie, D., Seibel, J., Ayuk, F., Friese, M. A., Heesen, C. & Kröger, N., 14.06.2024, In: MED-CAMBRIDGE. 5, 6, p. 550-558.e2Research output: SCORING: Contribution to journal › Case report › Research › peer-review
CD34 modulates the trafficking behavior of hematopoietic cells in vivo.
Lange, C., Li, Z., Fang, L., Baum, C. & Fehse, B., 2007, In: STEM CELLS DEV. 16, 2, p. 297-304 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD34(+)-selected stem cell boost for delayed or insufficient engraftment after allogeneic stem cell transplantation.
Oyekunle, A., Koehl, U., Schieder, H., Ayuketang Ayuk, F., Renges, H., Fehse, N., Zabelina, T., Fehse, B., Klingebiel, T., Sputtek, A., Zander, A. R. & Kröger, N., 2006, In: CYTOTHERAPY. 8, 4, p. 375-380 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD34 splice variant: an attractive marker for selection of gene-modified cells
Fehse, B., Richters, A., Putimtseva-Scharf, K., Klump, H., Li, Z., Ostertag, W., Zander, A. R. & Baum, C., 05.2000, In: MOL THER. 1, 5 Pt 1, p. 448-456 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD45-Directed CAR-T Cells with CD45 Knockout Efficiently Kill Myeloid Leukemia and Lymphoma Cells In Vitro Even after Extended Culture
Harfmann, M., Schröder, T., Głów, D., Jung, M., Uhde, A., Kröger, N., Horn, S., Riecken, K., Fehse, B. & Ayuk, F. A., 12.01.2024, In: CANCERS. 16, 2, 334.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation.
Atanackovic, D., Cao, Y., Luetkens, T., Panse, J., Faltz, C., Arfsten, J., Bartels, K., Wolschke, C., Eiermann, T., Zander, A. R., Fehse, B., Bokemeyer, C. & Kröger, N., 2008, In: HAEMATOLOGICA. 93, 3, p. 423-430 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertag (1937-2010).
Stocking, C., Grez, M., Fehse, B., von Laer, D., Itoh, K., Prassolov, V., Nowock, J., Kühlcke, K., Just, U., Schröder, T., Klump, H., Schiedlmeier, B., Grassman, E., Meyer, J., Li, Z., Schambach, A., Modlich, U., Kustikova, O., Galla, M., Jürgen, B., Zander, A. R. & Baum, C., 2010, In: HUM GENE THER. 21, 11, p. 1501-1503 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma
Roh, V., Abramowski, P., Hiou-Feige, A., Cornils, K., Rivals, J-P., Zougman, A., Aranyossy, T., Thielecke, L., Truan, Z., Mermod, M., Monnier, Y., Prassolov, V., Glauche, I., Nowrouzi, A., Abdollahi, A., Fehse, B., Simon, C. & Tolstonog, G. V., 20.11.2018, In: CELL REP. 25, 8, p. 2208-2222.e7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cellular Therapy with Engineered T Cells, Efficacy and Side Effects
Bondanza, A., Bonini, C., Fehse, B. & Hudecek, M., 2019, The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies: The EBMT Handbook. Carreras, E., Dufour, C., Mohty, M. & Kröger, N. (eds.). 1 ed. Springer Nature Switzerland AG, p. 449-456 8 p.Research output: SCORING: Contribution to book/anthology › Chapter › Research
Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-KPolymorphism
Braig, F., Kriegs, M., Voigtlaender, M., Habel, B., Grob, T., Biskup, K., Blanchard, V., Sack, M., Thalhammer, A., Ben Batalla, I., Braren, I., Laban, S., Danielczyk, A., Goletz, S., Jakubowicz, E., Märkl, B., Trepel, M., Knecht, R., Riecken, K., Fehse, B., Loges, S., Bokemeyer, C. & Binder, M., 01.03.2017, In: CANCER RES. 77, 5, p. 1188-1199 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chancen und Risiken der CAR-T-Zell-Therapie
Ayuk, F. A., Fehse, B., Berger, S. C., Riecken, K. & Kroger, N., 10.2019, In: Hamb Ärztebl. 73, 10, p. 30-32Research output: SCORING: Contribution to journal › SCORING: Review article › Education
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences
Baum, C., von Kalle, C., Staal, F. J. T., Li, Z., Fehse, B., Schmidt, M., Weerkamp, F., Karlsson, S., Wagemaker, G. & Williams, D. A., 01.2004, In: MOL THER. 9, 1, p. 5-13 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal
Grochowska, K. M., Sperveslage, M., Raman, R., Failla, A. V., Głów, D., Schulze, C., Laprell, L., Fehse, B. & Kreutz, M. R., 29.08.2023, In: CELL REP. 42, 8, p. 112998Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chimeric autoantibody receptor cell therapy for the treatment of membranous nephropathy: The authors reply
Fehse, B. & Tomas, N. M., 06.2024, In: KIDNEY INT. 105, 6, p. 1320-1321 2 p.Research output: SCORING: Contribution to journal › Letter › Research
Chimerism studies with quantitative real-time PCR in stem cell recipients with acute myeloid leukemia.
Wiedemann, B., Klyuchnikov, E., Kröger, N., Zabelina, T., Stahl, T., Zeschke, S., Badbaran, A., Ayuketang Ayuk, F., Alchalby, H., Wolschke, C., Bokemeyer, C., Fehse, B., Zander, A. R. & Bacher, U., 2010, In: EXP HEMATOL. 38, 12, p. 1261-1271 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical application of a retroviral gene transfer protocol based on centrifugation-mediated vector preloading.
Fehse, B., 2008, In: HUM GENE THER. 19, 6, p. 655-658 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion
Cornils, K., Thielecke, L., Winkelmann, D., Aranyossy, T., Lesche, M., Dahl, A., Roeder, I., Fehse, B. & Glauche, I., 14.07.2017, In: MOL CANCER. 16, 1, p. 120Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking
Kustikova, O., Fehse, B., Modlich, U., Yang, M., Düllmann, J., Kamino, K., von Neuhoff, N., Schlegelberger, B., Li, Z. & Baum, C., 20.05.2005, In: SCIENCE. 308, 5725, p. 1171-4 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks
Brenière-Letuffe, D., Domke-Shibamiya, A., Hansen, A., Eschenhagen, T., Fehse, B., Riecken, K. & Stenzig, J., 18.06.2018, In: STEM CELL RES THER. 9, 1, p. 165Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal Evolution after Allogeneic Hematopoietic Stem Cell Transplantation
Christopeit, M., Badbaran, A., Alawi, M., Flach, J., Fehse, B. & Kröger, N., 07.2020, In: BIOL BLOOD MARROW TR. 26, 7, p. e167-e170Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Combined Application of RGB Marking and Mass Spectrometric Imaging Facilitates Detection of Tumor Heterogeneity
Abramowski, P., Kraus, O., Rohn, S., Riecken, K., Fehse, B. & Schlüter, H., 03.07.2015, In: CANCER GENOM PROTEOM. 12, 4, p. 179-187 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review