Dr.med. ID: 3170422
Simone Zittel-Dirks
Publications
A case of Huntington's disease with two reduced penetrance alleles
Grimm, K., Zühlke, C., Gerloff, C. & Zittel, S., 08.2021, In: CLIN NEUROL NEUROSUR. 207, 106773.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Accidental intoxication with unlabeled, generic transdermal fentanyl patches caused by insufficient instruction]
Tank, S., Stork, K., Skibba, W., Zittel, S., Andresen, H., Goetz, A. E. & Beck, H., 2007, In: ANAESTHESIST. 56, 11, p. 1137-1141 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Activity parameters of subthalamic nucleus neurons selectively predict motor symptom severity in Parkinson's disease
Sharott, A., Gulberti, A., Zittel-Dirks, S., Tudor Jones, A. A., Fickel, U., Münchau, A., Köppen, J. A., Gerloff, C., Westphal, M., Buhmann, C., Hamel, W., Engel, A. K. & Moll, C. K. E., 2014, In: J NEUROSCI. 34, 18, p. 6273-6285 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A Multi-center Genome-wide Association Study of Cervical Dystonia
Sun, Y. V., Li, C., Hui, Q., Huang, Y., Barbano, R., Rodriguez, R., Malaty, I. A., Reich, S., Bambarger, K., Holmes, K., Jankovic, J., Patel, N. J., Roze, E., Vidailhet, M., Berman, B. D., LeDoux, M. S., Espay, A. J., Agarwal, P., Pirio-Richardson, S., Frank, S. A., Ondo, W. G., Saunders-Pullman, R., Chouinard, S., Natividad, S., Berardelli, A., Pantelyat, A. Y., Brashear, A., Fox, S. H., Kasten, M., Krämer, U. M., Neis, M., Bäumer, T., Loens, S., Borsche, M., Zittel, S., Maurer, A., Gelderblom, M., Volkmann, J., Odorfer, T., Kühn, A. A., Borngräber, F., König, I. R., Cruchaga, C., Cotton, A. C., Kilic-Berkmen, G., Freeman, A., Factor, S. A., Scorr, L., Bremner, J. D., Vaccarino, V., Quyyumi, A. A., Klein, C., Perlmutter, J. S., Lohmann, K. & Jinnah, H. A., 12.2021, In: MOVEMENT DISORD. 36, 12, p. 2795-2801 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A randomized, double-blind, placebo-controlled study of latrepirdine in patients with mild to moderate Huntington disease
HORIZON Investigators of the Huntington Study Group and European Huntington's Disease Network, 01.2013, In: JAMA NEUROL. 70, 1, p. 25-33 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Arm tremor in cervical dystonia--is it a manifestation of dystonia or essential tremor?
Schiebler, S., Schmidt, A., Zittel, S., Bäumer, T., Gerloff, C., Klein, C. & Münchau, A., 2011, In: MOVEMENT DISORD. 26, 10, p. 1789-1792 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Attenuated neural response to gamble outcomes in drug-naive patients with Parkinson's disease
van der Vegt, J. P. M., Hulme, O. J., Zittel-Dirks, S., Madsen, K. H., Weiss, M. M., Buhmann, C., Bloem, B. R., Münchau, A. & Siebner, H. R., 01.04.2013, In: BRAIN. 136, Pt 4, p. 1192-203 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Author response: Munchausen syndrome by genetics: Next-generation challenges for clinicians
Zittel, S., Alvarez-Fischer, D., Schweiger, U., Klein, C. & Münchau, A., 18.07.2017, In: NEUROLOGY. 89, 3, p. 307Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Cerebellar Modulation of Sensorimotor Associative Plasticity Is Impaired in Cervical Dystonia
Grimm, K., Prilop, L., Schön, G., Gelderblom, M., Misselhorn, J., Gerloff, C. & Zittel, S., 11.2023, In: MOVEMENT DISORD. 38, 11, p. 2084-2093 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterisation and differential diagnosis of neurological complications in adults with phenylketonuria: literature review and expert opinion
Merkel, M., Berg, D., Brüggemann, N., Classen, J., Mainka, T., Zittel, S. & Muntau, A. C., 08.2023, In: J NEUROL. 270, 8, p. 3675-3687 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Citalopram improves dexterity in chronic stroke patients.
Zittel, S., Weiller, C. & Liepert, J., 2008, In: NEUROREHAB NEURAL RE. 22, 3, p. 311-314 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical and neurophysiological profile of four German families with spinocerebellar ataxia type 14
Ganos, C., Zittel-Dirks, S., Minnerop, M., Schunke, O., Heinbokel, C., Gerloff, C., Zühlke, C., Bauer, P., Klockgether, T., Münchau, A. & Bäumer, T., 2014, In: CEREBELLUM. 13, 1, p. 89-96 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical neuroimaging and electrophysiological assessment of three DYT6 dystonia families.
Zittel, S., Moll, C., Brüggemann, N., Tadic, V., Hamel, W., Kasten, M., Lohmann, K., Lohnau, T., Winkler, S., Gerloff, C., Schönweiler, R., Hagenah, J., Klein, C., Münchau, A. & Schneider, S. A., 2010, In: MOVEMENT DISORD. 25, 14, p. 2405-2412 14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical, serological and genetic predictors of response to immunotherapy in anti-IgLON5 disease
Grüter, T., Möllers, F. E., Tietz, A., Dargvainiene, J., Melzer, N., Heidbreder, A., Strippel, C., Kraft, A., Höftberger, R., Schöberl, F., Thaler, F. S., Wickel, J., Chung, H-Y., Seifert, F., Tschernatsch, M., Nagel, M., Lewerenz, J., Jarius, S., Wildemann, B. C., de Azevedo, L., Heidenreich, F., Heusgen, R., Hofstadt-van Oy, U., Linsa, A., Maaß, J. J., Menge, T., Ringelstein, M., Pedrosa, D. J., Schill, J., Seifert-Held, T., Seitz, C., Tonner, S., Urbanek, C., Zittel, S., Markewitz, R., Korporal-Kuhnke, M., Schmitter, T., Finke, C., Brüggemann, N., Bien, C. I., Kleiter, I., Gold, R., Wandinger, K-P., Kuhlenbäumer, G., Leypoldt, F., Ayzenberg, I. & German Network for Research on Autoimmune Encephalitis (GENERATE), 13.02.2023, In: BRAIN. 146, 2, p. 600-611 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of Montreal cognitive assessment and Mattis dementia rating scale in the preoperative evaluation of subthalamic stimulation in Parkinson's disease
Gülke, E., Alsalem, M., Kirsten, M., Vettorazzi, E., Choe, C-U., Hidding, U., Zittel-Dirks, S., Buhmann, C., Schaper, M., Gulberti, A., Moll, C. K. E., Hamel, W., Koeppen, J., Gerloff, C. & Pötter-Nerger, M., 07.04.2022, In: PLOS ONE. 17, 4, e0265314.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deep brain stimulation of the ventrolateral thalamic base and posterior subthalamic area in dystonic head tremor
Buhmann, C., Moll, C. K. E., Zittel-Dirks, S., Münchau, A., Engel, A. K. & Hamel, W., 01.01.2013, In: ACTA NEUROCHIR SUPPL. 117, p. 67-72 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Differenzialdiagnose der atypischen Parkinson-Syndrome - Multisystematrophie, kortikobasales Syndrom, Lewy-Körper-Demenz
Zittel, S. & Münchau, A., 2012, In: Info Neurol Psych. 9, p. 48-55 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disability and persistent motor deficits are linked to structural crossed cerebellar diaschisis in chronic stroke
Guder, S., Sadeghi, F., Zittel, S., Quandt, F., Choe, C-U., Bönstrup, M., Cheng, B., Thomalla, G., Gerloff, C. & Schulz, R., 11.2023, In: HUM BRAIN MAPP. 44, 16, p. 5336-5345 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dystonia as initial presentation of compound heterozygous GBA2 mutations: Expanding the phenotypic spectrum of SPG46
Kloth-Stachnau, K., Cozma, C., Bester, M., Gerloff, C., Biskup, S. & Zittel, S., 09.2020, In: EUR J MED GENET. 63, 9, p. 103992Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effects of dopaminergic treatment on functional cortico-cortical connectivity in Parkinson's disease
Zittel-Dirks, S., Heinbokel, C., van der Vegt, J. P. M., Niessen, E., Buhmann, C., Gerloff, C., Siebner, H. R., Münchau, A. & Bäumer, T., 01.01.2015, In: EXP BRAIN RES. 233, 1, p. 329-37 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Episodic ataxias
Zittel, S. & Ganos, C., 2020, Paroxysmal Movement Disorders: A Practical, Concise Guide. Sethi, K. D., Erro, R. & Bhatia, K. P. (eds.). 1 ed. Springer Nature, p. 133-140 14 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Frequency of non-motor symptoms in Parkinson's disease patients carrying the E326K and T369M GBA risk variants
Usnich, T., Olmedillas, M., Schell, N., Paul, J. J., Curado, F., Skobalj, S., Csoti, I., Ertan, S., Gruber, D., Zittel, S., Sammler, E., Isaacson, S. H., Kühn, A. A., Pedrosa, D. J., Reetz, K., Kasten, M., Rolfs, A., Bauer, P., Skrahina, V., Klein, C., Brüggemann, N. & LIPAD Study Group, 02.2023, In: PARKINSONISM RELAT D. 107, p. 105248Research output: SCORING: Contribution to journal › Letter › Research › peer-review
Genome-wide association study in musician's dystonia: a risk variant at the arylsulfatase G locus?
Lohmann, K., Schmidt, A., Schillert, A., Winkler, S., Albanese, A., Baas, F., Bentivoglio, A. R., Borngräber, F., Brüggemann, N., Defazio, G., Del Sorbo, F., Deuschl, G., Edwards, M. J., Gasser, T., Gómez-Garre, P., Graf, J., Groen, J. L., Grünewald, A., Hagenah, J., Hemmelmann, C., Jabusch, H-C., Kaji, R., Kasten, M., Kawakami, H., Kostic, V. S., Liguori, M., Mir, P., Münchau, A., Ricchiuti, F., Schreiber, S., Siegesmund, K., Svetel, M., Tijssen, M. A. J., Valente, E. M., Westenberger, A., Zeuner, K. E., Zittel, S., Altenmüller, E., Ziegler, A. & Klein, C., 06.2014, In: MOVEMENT DISORD. 29, 7, p. 921-7 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genotype-phenotype correlation and treatment effects in young patients with GNAO1-associated disorders
Thiel, M., Bamborschke, D., Janzarik, W. G., Assmann, B., Zittel, S., Patzer, S., Auhuber, A., Opp, J., Matzker, E., Bevot, A., Seeger, J., van Baalen, A., Stüve, B., Brockmann, K., Cirak, S. & Koy, A., 10.2023, In: J NEUROL NEUROSUR PS. 94, 10, p. 806-815 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HbA1c and Motor Outcome in Parkinson's Disease in the Mark-PD Study
Zittel, S., Uyar, M., Lezius, S., Gerloff, C. & Choe, C-U., 08.2021, In: MOVEMENT DISORD. 36, 8, p. 1991-1992 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
How does it feel to be operated on the brain? Perceived intraoperative stress of movement disorder patients undergoing awake deep brain stimulation surgery
Sieger, J., Gulberti, A., Köppen, J., Pinnschmidt, H., Nitzschke, R., Schaper, M., Braaß, H., Buhmann, C., Choe, C., Hidding, U., Zittel, S., Engel, A. K., Mehnert, A., Gerloff, C., Westphal, M., Pötter-Nerger, M., Hamel, W. & Moll, C., 16.03.2018, The many faces of Parkinson’s disease – Motor and non ‐ motor symptoms from prodromal to advanced disease stages.Research output: SCORING: Contribution to book/anthology › Conference contribution - Poster › Research
Identification and functional analysis of novel THAP1 mutations.
Lohmann, K., Uflacker, N., Erogullari, A., Lohnau, T., Winkler, S., Dendorfer, A., Schneider, S. A., Osmanovic, A., Svetel, M., Ferbert, A., Zittel, S., Kühn, A. A., Schmidt, A., Altenmüller, E., Münchau, A., Kamm, C., Wittstock, M., Kupsch, A., Moro, E., Volkmann, J., Kostic, V., Kaiser, F. J., Klein, C. & Brüggemann, N., 2012, In: EUR J HUM GENET. 20, 2, p. 171-175 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired Metacognition of Voluntary Movement in Functional Movement Disorder
Verrel, J., Chwolka, F., Filevich, E., Moyé, J., Paulus, T., Zittel, S., Bäumer, T., Münchau, A. & Weissbach, A., 03.2023, In: MOVEMENT DISORD. 38, 3, p. 435-443 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Improvement of dexterity by single session low-frequency repetitive transcranial magnetic stimulation over the contralesional motor cortex in acute stroke: a double-blind placebo-controlled crossover trial.
Liepert, J., Zittel, S. & Weiller, C., 2007, In: RESTOR NEUROL NEUROS. 25, 5-6, p. 461-465 5-6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inhibitory and facilitatory connectivity from ventral premotor to primary motor cortex in healthy humans at rest--a bifocal TMS study.
Bäumer, T., Schippling, S., Kröger, J., Zittel, S., Koch, G., Thomalla, G., Rothwell, J. C., Siebner, H. R., Orth, M. & Münchau, A., 2009, In: CLIN NEUROPHYSIOL. 120, 9, p. 1724-1731 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IRF2BPL mutation causes nigrostriatal degeneration presenting with dystonia, spasticity and keratoconus
Prilop, L., Buchert, R., Woerz, S., Gerloff, C., Haack, T. B. & Zittel, S., 09.04.2020, In: PARKINSONISM RELAT D. 79, p. 141-143Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
IRF2BPL mutations cause autosomal dominant dystonia with anarthria, slow saccades and seizures
Ganos, C., Zittel, S., Hidding, U., Funke, C., Biskup, S. & Bhatia, K. P., 11.2019, In: PARKINSONISM RELAT D. 68, p. 57-59 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Iron overload is accompanied by mitochondrial and lysosomal dysfunction in WDR45 mutant cells
Seibler, P., Burbulla, L. F., Dulovic, M., Zittel, S., Heine, J., Schmidt, T., Rudolph, F., Westenberger, A., Rakovic, A., Münchau, A., Krainc, D. & Klein, C., 01.10.2018, In: BRAIN. 141, 10, p. 3052-3064 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Linking Penetrance and Transcription in DYT-THAP1: Insights From a Human iPSC-Derived Cortical Model
Baumann, H., Ott, F., Weber, J., Trilck-Winkler, M., Münchau, A., Zittel, S., Kostić, V. S., Kaiser, F. J., Klein, C., Busch, H., Seibler, P. & Lohmann, K., 06.2021, In: MOVEMENT DISORD. 36, 6, p. 1381-1391 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
LIPAD (LRRK2/Luebeck International Parkinson's Disease) Study Protocol: Deep Phenotyping of an International Genetic Cohort
Usnich, T., Vollstedt, E-J., Schell, N., Skrahina, V., Bogdanovic, X., Gaber, H., Förster, T. M., Heuer, A., Koleva-Alazeh, N., Csoti, I., Basak, A. N., Ertan, S., Genc, G., Bauer, P., Lohmann, K., Grünewald, A., Schymanski, E. L., Trinh, J., Schaake, S., Berg, D., Gruber, D., Isaacson, S. H., Kühn, A. A., Mollenhauer, B., Pedrosa, D. J., Reetz, K., Sammler, E. M., Valente, E. M., Valzania, F., Volkmann, J., Zittel, S., Brüggemann, N., Kasten, M., Rolfs, A., Klein, C. & LIPAD Study Group, 2021, In: FRONT NEUROL. 12, 710572.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Modulation of intracortical facilitatory circuits of the human primary motor cortex by digital nerve stimulation.
Zittel, S., Bäumer, T. & Liepert, J., 2007, In: EXP BRAIN RES. 176, 3, p. 425-431 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Modulation of motor cortex excitability induced by pinch grip repetition.
Gorsler, A., Zittel, S., Weiller, C., Münchau, A. & Liepert, J., 2004, In: J NEURAL TRANSM. 111, 8, p. 1005-1016 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Motor pathway excitability in ATP13A2 mutation carriers: a transcranial magnetic stimulation study.
Zittel, S., Kröger, J., van der Vegt, J. P. M., Siebner, H. R., Brüggemann, N., Ramirez, A., Behrens, M. I., Gerloff, C., Bäumer, T., Klein, C. & Münchau, A., 2012, In: PARKINSONISM RELAT D. 18, 5, p. 590-594 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Motor strokes: the lesion location determines motor excitability changes.
Liepert, J., Restemeyer, C., Kucinski, T., Zittel, S. & Weiller, C., 2005, In: STROKE. 36, 12, p. 2648-2653 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multisystemic neurodegeneration caused by biallelic pentanucleotide expansions in RFC1
Herrmann, L., Gelderblom, M., Bester, M., Deininger, N., Schütze, T., Hidding, U., Gross, C., Buena-Atienza, E., Dufke, C., Gerloff, C., Haack, T. B. & Zittel, S., 02.2022, In: PARKINSONISM RELAT D. 95, p. 54-56 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Munchausen syndrome by genetics: Next-generation challenges for clinicians
Zittel, S., Lohmann, K., Bauer, P., Klein, C. & Münchau, A., 07.03.2017, In: NEUROLOGY. 88, 10, p. 1000-1001Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Mutant WDR45 Leads to Altered Ferritinophagy and Ferroptosis in β-Propeller Protein-Associated Neurodegeneration
Diaw, S. H., Ganos, C., Zittel, S., Plötze-Martin, K., Kulikovskaja, L., Vos, M., Westenberger, A., Rakovic, A., Lohmann, K. & Dulovic-Mahlow, M., 23.08.2022, In: INT J MOL SCI. 23, 17, 9524.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutations in THAP1 (DYT6) and generalised dystonia with prominent spasmodic dysphonia: a genetic screening study.
Djarmati, A., Schneider, S. A., Lohmann, K., Winkler, S., Pawlack, H., Hagenah, J., Brüggemann, N., Zittel, S., Fuchs, T., Rakovi, A., Schmidt, A., Jabusch, H-C., Wilcox, R., Kosti, V. S., Siebner, H., Altenmüller, E., Münchau, A., Ozelius, L. J. & Klein, C., 2009, In: LANCET NEUROL. 8, 5, p. 447-452 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neues bei paroxysmalen Bewegungsstörungen
Zittel, S. & Münchau, A., 2012, In: AKTUEL NEUROL. 39, 09, p. 463-466 09.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neurophysiological fingerprints of X-linked dystonia-parkinsonism: A model basal ganglia disease
Weissbach, A., Bäumer, T., Rosales, R., Lee, L. V., Brüggemann, N., Domingo, A., Westenberger, A., Jamora, R. D., Diesta, C. C., Brandt, V., Tadic, V., Zittel, S., Klein, C. & Münchau, A., 05.2015, In: MOVEMENT DISORD. 30, 6, p. 873-5 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Normalization of sensorimotor integration by repetitive transcranial magnetic stimulation in cervical dystonia
Zittel, S., Helmich, R. C. G., Demiralay, C., Münchau, A. & Bäumer, T., 08.2015, In: J NEUROL. 262, 8, p. 1883-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Optimizing the montage for cerebellar transcranial alternating current stimulation (tACS): a combined computational and experimental study
Sadeghihassanabadi, F., Misselhorn, J., Gerloff, C. & Zittel, S., 04.05.2022, In: J NEURAL ENG. 19, 2, 026060.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pallidal deep brain stimulation in Huntington's disease
Zittel-Dirks, S., Moll, C. K. E., Gulberti, A., Tadic, V., Rasche, D., Bäumer, T., Fellbrich, A., Brüggemann, N., Engel, A. K., Tronnier, V., Hamel, W. & Münchau, A., 09.2015, In: PARKINSONISM RELAT D. 21, 9, p. 1105-8 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Pallidal lead placement in dystonia: leads of non-responders are contained within an anatomical range defined by responders
Zittel, S., Hidding, U., Trumpfheller, M., Baltzer, V. L., Gulberti, A., Schaper, M., Biermann, M., Buhmann, C., Engel, A. K., Gerloff, C., Westphal, M., Stadler, J., Köppen, J. A., Pötter-Nerger, M., Moll, C. K. E. & Hamel, W., 06.2020, In: J NEUROL. 267, 6, p. 1663-1671 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Paroxysmal cervical myoclonus.
Zittel, S., Bäumer, T., Brüggemann, N., Gerloff, C., Klein, C. & Münchau, A., 2011, In: MOVEMENT DISORD. 26, 13, p. 2445-2446 13.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review