Prof. Dr. ID: 63094

Martin Aepfelbacher

Head of Clinic

graph of relations

Publications

  1. 2024
  2. A multicenter study of asymmetric and symmetric dimethylarginine as predictors of mortality risk in hospitalized COVID-19 patients

    Hannemann, J., Zink, A., Mileva, Y., Balfanz, P., Dahl, E., Volland, S., Illig, T., Schwedhelm, E., Kurth, F., Stege, A., Aepfelbacher, M., Hoffmann, A. & Böger, R., 08.07.2024, In: SCI REP-UK. 14, 1, p. 15739

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Adaptation and validation of a quantitative vanA/vanB DNA screening assay on a high-throughput PCR system

    Giersch, K., Tanida, K., Both, A., Nörz, D., Heim, D., Rohde, H., Aepfelbacher, M. & Lütgehetmann, M., 12.02.2024, In: SCI REP-UK. 14, 1, p. 3523

    Research output: SCORING: Contribution to journalSCORING: Journal articleTransferpeer-review

  4. The added value of (1,3)-β-D-glucan for the diagnosis of Invasive Candidiasis in ICU patients: a prospective cohort study

    Christner, M., Abdennadher, B., Wichmann, D., Kluge, S., Pepić, A., Aepfelbacher, M., Rohde, H. & Olearo, F., 02.2024, In: INFECTION. 52, 1, p. 73-81 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. 2023
  6. A bacterial effector protein promotes nuclear translocation of Stat3 to induce IL-10.

    Berneking, L., Bekere, I., Rob, S., Schnapp, M., Huang, J., Ruckdeschel, K. & Aepfelbacher, M., 12.2023, In: EUR J CELL BIOL. 102, 4, p. 151364 151364.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Complete genome sequence of a Staphylococcus condimenti isolated from a port catheter-associated bloodstream infection

    Berneking, L., Büttner, H., Qi, M., Günther, T., Lehnhoff, D., Both, A., Christner, M., Wolters, M., Alawi, M., Aepfelbacher, M. & Rohde, H., 19.10.2023, In: MICROBIOL RESOUR ANN. 12, 10, 3 p., e0043823.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  8. Performance and Hypothetical Impact on Joint Infection Management of the BioFire Joint Infection Panel: a Retrospective Analysis

    Berinson, B., Spenke, L., Krivec, L., Tanida, K., Both, A., Keller, J., Rolvien, T., Christner, M., Lütgehetmann, M., Aepfelbacher, M., Klatte, T. O. & Rohde, H., 23.08.2023, In: Journal of Clinical Microbiology. 61, 8, e0059223.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Epidemiology of co-infections in pregnant women living with human immunodeficiency virus 1 in rural Gabon: a cross-sectional study

    Davi, S. D., Okwu, D. G., Luetgehetmann, M., Abba, F. M., Aepfelbacher, M., Endamne, L. R., Alabi, A., Zoleko-Manego, R., Mombo-Ngoma, G., Mahmoudou, S., Addo, M. M., Ramharter, M. & Mischlinger, J., 06.07.2023, In: INFECT DIS POVERTY. 12, 1, 64.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  10. First case of bloodstream infection caused by Mixta hanseatica sp. nov., a novel species within the Mixta genus of the Erwiniaceae family

    Both, A., Huang, J., Wenzel, P., Aepfelbacher, M., Rohde, H., Christner, M. & Hentschke, M., 06.2023, In: NEW MICROB NEW INFEC. 53, p. 101117 101117.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  11. The Impact of Antimicrobial Therapy Duration in the Treatment of Prosthetic Joint Infections Depending on Surgical Strategies:A Systematic Review and Meta-analysis

    Olearo, F., Zanichelli, V., Exarchakou, A., Both, A., Uςkay, I., Aepfelbacher, M. & Rohde, H., 05.2023, In: OPEN FORUM INFECT DI. 10, 5, ofad246.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  12. Genomics of Invasive Cutibacterium acnes Isolates from Deep-Seated Infections

    Both, A., Huang, J., Hentschke, M., Tobys, D., Christner, M., Klatte, T. O., Seifert, H., Aepfelbacher, M. & Rohde, H., 28.03.2023, In: MICROBIOL SPECTR. 11, 2, p. e0474022

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany

    Heinrich, F., Huter, T., Mertens, S., Lange, P., Vering, J., Heinemann, A., Nörz, D. S., Hoffmann, A., Aepfelbacher, M., Ondruschka, B., Krasemann, S. & Lütgehetmann, M., 03.2023, In: EMERG INFECT DIS. 29, 3, p. 652-656 5 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  14. Performance of an interferon-γ release assay-based test for cell-mediated immunity to SARS-CoV-2

    Fonseca, B. L., Tödter, S., Kottlau, J., Cermann, K., Spier, A., Petersen, E., Schäfer, I., Twerenbold, R., Aepfelbacher, M., Lütgehetmann, M. & Stahl, FR., 16.02.2023, In: FRONT IMMUNOL. 14, p. 1069968

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Integration of Sequencing and Epidemiologic Data for Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections in a Tertiary-Care Hospital

    Czech-Sioli, M., Günther, T., Robitaille, A., Roggenkamp, H., Büttner, H., Indenbirken, D., Christner, M., Lütgehetmann, M., Knobloch, J., Aepfelbacher, M., Grundhoff, A. & Fischer, N., 08.02.2023, In: CLIN INFECT DIS. 76, 3, p. e263-e273

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. MINFLUX imaging of a bacterial molecular machine at nanometer resolution

    Carsten, A., Rudolph, M., Weihs, T., Schmidt, R., Jansen, I., Wurm, C. A., Diepold, A., Failla, A. V., Wolters, M. & Aepfelbacher, M., 01.2023, In: METHODS APPL FLUORES. 11, 1, 015004.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. 2022
  18. Infectivity of SARS-CoV-2 on Inanimate Surfaces: Don't Trust Ct Value

    Knobloch, J. K., Pfefferle, S., Lütgehetmann, M., Nörz, D., Klupp, E. M., Belmar Campos, C. E., Kluge, S., Aepfelbacher, M., Knobling, B. & Franke, G., 19.12.2022, In: INT J ENV RES PUB HE. 19, 24, 17074.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive

    Zielinski, K. A., Prester, A., Andaleeb, H., Bui, S., Yefanov, O., Catapano, L., Henkel, A., Wiedorn, M. O., Lorbeer, O., Crosas, E., Meyer, J., Mariani, V., Domaracky, M., White, T. A., Fleckenstein, H., Sarrou, I., Werner, N., Betzel, C., Rohde, H., Aepfelbacher, M., Chapman, H. N., Perbandt, M., Steiner, R. A. & Oberthuer, D., 01.11.2022, In: IUCRJ. 9, Pt 6, p. 778-791 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Clinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus

    Nörz, D., Brehm, T. T., Tang, H. T., Grewe, I., Hermanussen, L., Matthews, H., Pestel, J., Degen, O., Günther, T., Grundhoff, A., Fischer, N., Addo, M. M., Jordan, S., Hertling, S., Unger, S., Schäfer, G., Schewe, K., Hoffmann, C., Aepfelbacher, M., Pfefferle, S., Schulze Zur Wiesch, J., Schmiedel, S. & Lütgehetmann, M., 10.2022, In: J CLIN VIROL. 155, 105254.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants

    Brehm, T. T., Pfefferle, S., von Possel, R., Karolyi, M., Zoufaly, A., Wichmann, D., Kobbe, R., Emmerich, P., Nörz, D., Aepfelbacher, M., Schulze Zur Wiesch, J., Addo, M. M., Schmiedel, S. & Lütgehetmann, M., 10.2022, In: J MED VIROL. 94, 10, p. 5038-5043 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection

    Heyer, A., Günther, T., Robitaille, A., Lütgehetmann, M., Addo, M. M., Jarczak, D., Kluge, S., Aepfelbacher, M., Schulze Zur Wiesch, J., Fischer, N. & Grundhoff, A., 20.09.2022, In: CELL REP MED. 3, 9, 100735.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Anti-SARS-CoV-2 antibodies in breast milk during lactation after infection or vaccination: A cohort study

    Olearo, F., Radmanesh, L-S., Felber, N., von Possel, R., Emmerich, P., Pekarek, N., Pfefferle, S., Nörz, D., Hansen, G., Diemert, A., Aepfelbacher, M., Hecher, K., Lütgehetmann, M., Arck, P. C. & Tallarek, A-C., 09.2022, In: J REPROD IMMUNOL. 153, 103685.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus

    Paulowski, L., Beckham, K. S. H., Johansen, M. D., Berneking, L., Van, N., Degefu, Y., Staack, S., Sotomayor, F. V., Asar, L., Rohde, H., Aldridge, B. B., Aepfelbacher, M., Parret, A., Wilmanns, M., Kremer, L., Combrink, K. & Maurer, F. P., 09.2022, In: PNAS nexus. 1, 4, pgac130.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19

    Casagrande, M., Fitzek, A., Spitzer, M., Püschel, K., Glatzel, M., Krasemann, S., Aepfelbacher, M., Nörz, D., Lütgehetmann, M., Pfefferle, S. & Spitzer, M., 09.2022, In: BRIT J OPHTHALMOL. 106, 9, p. 1313-1317 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection

    Nörz, D., Tang, H. T., Emmerich, P., Giersch, K., Fischer, N., Schmiedel, S., Addo, M. M., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 09.2022, In: EMERG INFECT DIS. 28, 9, p. 1765-1769 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?

    Jonigk, D., Werlein, C., Acker, T., Aepfelbacher, M., Amann, K. U., Baretton, G., Barth, P., Bohle, R. M., Büttner, A., Büttner, R., Dettmeyer, R., Eichhorn, P., Elezkurtaj, S., Esposito, I., Evert, K., Evert, M., Fend, F., Gaßler, N., Gattenlöhner, S., Glatzel, M., Göbel, H., Gradhand, E., Hansen, T., Hartmann, A., Heinemann, A., Heppner, F. L., Hilsenbeck, J., Horst, D., Kamp, J. C., Mall, G., Märkl, B., Ondruschka, B., Pablik, J., Pfefferle, S., Quaas, A., Radbruch, H., Röcken, C., Rosenwald, A., Roth, W., Rudelius, M., Schirmacher, P., Slotta-Huspenina, J., Smith, K., Sommer, L., Stock, K., Ströbel, P., Strobl, S., Titze, U., Weirich, G., Weis, J., Werner, M., Wickenhauser, C., Wiech, T., Wild, P., Welte, T., von Stillfried, S. & Boor, P., 08.2022, In: VIRCHOWS ARCH. 481, 2, p. 139-159 21 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  28. Update zur kooperativen autopsiebasierten Forschung in der deutschen Pathologie, Neuropathologie und Gerichtsmedizin

    von Stillfried, S., Freeborn, B., Windeck, S., Boor, P. & DeRegCOVID and NATON, 08.2022, In: PATHOLOGIE. 43, Suppl 1, p. 101-105 5 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  29. Three Separate Spike Antigen Exposures by COVID-19 Vaccination or SARS-CoV-2 Infection Elicit Strong Humoral Immune Responses in Healthcare Workers

    Brehm, T. T., Ullrich, F., Thompson, M., Küchen, J., Schwinge, D., Spier, A., Huber, S., Knobloch, J. K., Aepfelbacher, M., Addo, M. M., Lohse, A. W., Lütgehetmann, M. & Schulze Zur Wiesch, J., 06.07.2022, In: VACCINES-BASEL. 10, 7, 1086.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Live imaging of Yersinia translocon formation and immune recognition in host cells

    Rudolph, M., Carsten, A., Kulnik, S., Aepfelbacher, M. & Wolters, M., 05.2022, In: PLOS PATHOG. 18, 5, e1010251.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as β-lactamase inhibitors

    Perbandt, M., Werner, N., Prester, A., Rohde, H., Aepfelbacher, M., Hinrichs, W. & Betzel, C., 01.04.2022, In: SCI REP-UK. 12, 1, 5510.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. First report from the German COVID-19 autopsy registry

    von Stillfried, S., Bülow, R. D., Röhrig, R., Boor, P. & German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators, 04.2022, In: LANCET REG HEALTH-EU. 15, 100330.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report

    von Stillfried, S., Bülow, R. D., Röhrig, R., Meybohm, P., Boor, P. & German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators, 28.03.2022, In: CRIT CARE. 26, 1, 83.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants

    Nörz, D., Grunwald, M., Tang, H. T., Weinschenk, C., Günther, T., Robitaille, A., Giersch, K., Fischer, N., Grundhoff, A., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 15.03.2022, In: VIRUSES-BASEL. 14, 3, 608.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Comparing susceptibility and contagiousness in concurrent outbreaks with a non-VOC and the VOC SARS-CoV-2 variant B.1.1.7 in daycare centers in Hamburg, Germany

    Nakel, J., Robitaille, A., Günther, T., Rosenau, L., Czech-Sioli, M., Plenge-Bönig, A., Bühler, S., Wille, A., Jakubowski, E., Pruskil, S., Wahlen, M., Indenbirken, D., Nörz, D., Lütgehetmann, M., Aepfelbacher, M., Grundhoff, A., Grolle, B. & Fischer, N., 03.2022, In: INT J HYG ENVIR HEAL. 240, 113928.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Evaluation of a syndromic panel polymerase chain reaction (spPCR) assay for the diagnosis of device associated bone and joint infections (BJI)

    Berneking, L., Haas, M., Frielinghaus, L., Berinson, B., Lütgehetmann, M., Christner, M., Aepfelbacher, M., Gerlach, U., Seide, K., Both, A. & Rohde, H., 03.2022, In: INT J INFECT DIS. 116, p. 283-288 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Molecular consequences of SARS-CoV-2 liver tropism

    Wanner, N., Andrieux, G., Badia-I-Mompel, P., Edler, C., Pfefferle, S., Lindenmeyer, M. T., Schmidt-Lauber, C., Czogalla, J., Wong, M. N., Okabayashi, Y., Braun, F., Lütgehetmann, M., Meister, E., Lu, S., Noriega, M. L. M., Günther, T., Grundhoff, A., Fischer, N., Bräuninger, H., Lindner, D., Westermann, D., Haas, F., Roedl, K., Kluge, S., Addo, M. M., Huber, S., Lohse, A. W., Reiser, J., Ondruschka, B., Sperhake, J. P., Saez-Rodriguez, J., Boerries, M., Hayek, S. S., Aepfelbacher, M., Scaturro, P., Puelles, V. G. & Huber, T. B., 03.2022, In: NAT METAB. 4, 3, p. 310-319 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Population dynamics in colonizing vancomycin-resistant Enterococcus faecium isolated from immunosuppressed patients

    Both, A., Kruse, F., Mirwald, N., Franke, G., Christner, M., Huang, J., Hansen, J. L., Kröger, N., Berneking, L., Lellek, H., Aepfelbacher, M. & Rohde, H., 03.2022, In: J GLOB ANTIMICROB RE. 28, p. 267-273 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths

    Heinrich, F., Schröder, A. S., Gerberding, A-L., Gerling, M., Langenwalder, F., Lange, P., Heinemann, A., Bibiza-Freiwald, E., Nörz, D. S., Aepfelbacher, M., Pfefferle, S., Ondruschka, B. & Lütgehetmann, M., 01.2022, In: EMERG INFECT DIS. 28, 1, p. 244-247 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  40. Development of an artificial synovial fluid useful for studying Staphylococcus epidermidis joint infections

    Stamm, J., Weißelberg, S., Both, A., Failla, A. V., Nordholt, G., Büttner, H., Linder, S., Aepfelbacher, M. & Rohde, H., 2022, In: FRONT CELL INFECT MI. 12, 948151.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. 2021
  42. Polymicrobial enteric infections in african infants with diarrhoea - Results from a longitudinal prospective case-control study

    Heinemann, M., Strauchs, C., Lütgehetmann, M., Aepfelbacher, M., Klupp, E-M., Owusu-Dabo, E., Rolling, T., Cramer, J. P. & Vinnemeier, C. D., 12.2021, In: CLIN MICROBIOL INFEC. 27, 12, p. 1792-1798 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Multiorgan tropism of SARS-CoV-2 lineage B.1.1.7

    Ondruschka, B., Heinrich, F., Lindenmeyer, M., Edler, C., Möbius, D., Czogalla, J., Heinemann, A., Braun, F., Aepfelbacher, M., Lütgehetmann, M. & Huber, T. B., 11.2021, In: INT J LEGAL MED. 135, 6, p. 2347-2349 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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