Research ExplorerScientific StaffJan Broder Engler Publications

Dr. ID: 48675

Jan Broder Engler

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Affiliations
ORCID: 0000-0002-3169-2076
1 - 25 out of 25Page size: 50

Publications

  1. 2024

  2. Ferroptosis in health and disease

    Berndt, C., Alborzinia, H., Amen, V. S., Ayton, S., Barayeu, U., Bartelt, A., Bayir, H., Bebber, C. M., Birsoy, K., Böttcher, J. P., Brabletz, S., Brabletz, T., Brown, A. R., Brüne, B., Bulli, G., Bruneau, A., Chen, Q., DeNicola, G. M., Dick, T. P., Distéfano, A., Dixon, S. J., Engler, J. B., Esser-von Bieren, J., Fedorova, M., Friedmann Angeli, J. P., Friese, M. A., Fuhrmann, D. C., García-Sáez, A. J., Garbowicz, K., Götz, M., Gu, W., Hammerich, L., Hassannia, B., Jiang, X., Jeridi, A., Kang, Y. P., Kagan, V. E., Konrad, D. B., Kotschi, S., Lei, P., Le Tertre, M., Lev, S., Liang, D., Linkermann, A., Lohr, C., Lorenz, S., Luedde, T., Methner, A., Michalke, B., Milton, A. V., Min, J., Mishima, E., Müller, S., Motohashi, H., Muckenthaler, M. U., Murakami, S., Olzmann, J. A., Pagnussat, G., Pan, Z., Papagiannakopoulos, T., Pedrera Puentes, L., Pratt, D. A., Proneth, B., Ramsauer, L., Rodriguez, R., Saito, Y., Schmidt, F., Schmitt, C., Schulze, A., Schwab, A., Schwantes, A., Soula, M., Spitzlberger, B., Stockwell, B. R., Thewes, L., Thorn-Seshold, O., Toyokuni, S., Tonnus, W., Trumpp, A., Vandenabeele, P., Vanden Berghe, T., Venkataramani, V., Vogel, F. C. E., von Karstedt, S., Wang, F., Westermann, F., Wientjens, C., Wilhelm, C., Wölk, M., Wu, K., Yang, X., Yu, F., Zou, Y. & Conrad, M., 09.2024, In: REDOX BIOL. 75, 103211.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  3. The neuropathobiology of multiple sclerosis

    Woo, M. S., Engler, J. B. & Friese, M. A., 07.2024, In: NAT REV NEUROSCI. 25, 7, p. 493-513 21 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  4. Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis

    Winschel, I., Willing, A., Engler, J. B., Walkenhorst, M., Meurs, N., Binkle-Ladisch, L., Woo, M. S., Pfeffer, L. K., Sonner, J. K., Borgmeyer, U., Hagen, S. H., Grünhagel, B., Claussen, J. M., Altfeld, M. & Friese, M. A., 15.05.2024, In: BIOL SEX DIFFER. 15, 1, p. 41

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. 2023

  6. MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration

    Winkler, I., Engler, J. B., Vieira, V., Bauer, S., Liu, Y-H., Di Liberto, G., Grochowska, K. M., Wagner, I., Bier, J., Bal, L. C., Rothammer, N., Meurs, N., Egervari, K., Schattling, B., Salinas, G., Kreutz, M. R., Huang, Y-S., Pless, O., Merkler, D. & Friese, M. A., 24.11.2023, In: SCI ADV. 9, 47, eadi6855.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells

    Woo, M. S., Ufer, F., Sonner, J. K., Belkacemi, A., Tintelnot, J., Sáez, P. J., Krieg, P. F., Mayer, C., Binkle-Ladisch, L., Engler, J. B., Bauer, S., Kursawe, N., Vieira, V., Mannebach, S., Freichel, M., Flockerzi, V., Vargas, P. & Friese, M. A., 22.09.2023, In: SCI ADV. 9, 38, eadh1653.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. GPR52 regulates cAMP in T cells but is dispensable for encephalitogenic responses

    Krieg, P. F., Sonner, J. K., Kurelic, R., Engler, J. B., Scharenberg, M. F., Bauer, S., Nikolaev, V. O. & Friese, M. A., 24.01.2023, In: FRONT IMMUNOL. 13, 1113348.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. 2022

  10. G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis

    Rothammer, N., Woo, M. S., Bauer, S., Binkle-Ladisch, L., Di Liberto, G., Egervari, K., Wagner, I., Haferkamp, U., Pless, O., Merkler, D., Engler, J. B. & Friese, M. A., 05.08.2022, In: SCI ADV. 8, 31, eabm5500.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. 2021

  12. Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation

    Woo, M. S., Ufer, F., Rothammer, N., Di Liberto, G., Binkle, L., Haferkamp, U., Sonner, J. K., Engler, J. B., Hornig, S., Bauer, S., Wagner, I., Egervari, K., Raber, J., Duvoisin, R. M., Pless, O., Merkler, D. & Friese, M. A., 03.05.2021, In: J EXP MED. 218, 5, e20201290.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis

    Kaufmann, M., Evans, H., Schaupp, A-L., Engler, J. B., Kaur, G., Willing, A., Kursawe, N., Schubert, C., Attfield, K. E., Fugger, L. & Friese, M., 12.03.2021, In: MED-CAMBRIDGE. 2, 3, p. 296-312.e8

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis

    Rosenkranz, S. C., Shaposhnykov, A., Träger, S., Engler, J. B., Witte, M. E., Roth, V., Vieira, V., Paauw, N., Bauer, S., Schwencke-Westphal, C., Schubert, C., Bal, L., Schattling, B., Pless, O., van Horssen, J., Freichel, M. & Friese, M., 10.02.2021, In: ELIFE. 10, p. e61798 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. 2020

  16. Voltage-Gated Proton Channel Hv1 Controls TLR9 Activation in Plasmacytoid Dendritic Cells

    Montes-Cobos, E., Huscher, B., Engler, J. B., Woo, M. S., Binkle, L., Bauer, S., Kursawe, N., Moles, M., Friese, M. A. & Ufer, F., 01.12.2020, In: J IMMUNOL. 205, 11, p. 3001-3010 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Motor neuron translatome reveals deregulation of SYNGR4 and PLEKHB1 in mutant TDP-43 amyotrophic lateral sclerosis models

    Marques, R. F., Engler, J. B., Küchler, K., Jones, R. A., Lingner, T., Salinas, G., Gillingwater, T. H., Friese, M. A. & Duncan, K. E., 29.09.2020, In: HUM MOL GENET. 29, 16, p. 2647-2661 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. 2019

  19. T Cell Repertoire Dynamics during Pregnancy in Multiple Sclerosis

    Ramien, C., Yusko, E. C., Engler, J. B., Gamradt, S., Patas, K., Schweingruber, N., Willing, A., Rosenkranz, S. C., Diemert, A., Harrison, A., Vignali, M., Sanders, C., Robins, H. S., Tolosa, E., Heesen, C., Arck, P. C., Scheffold, A., Chan, K., Emerson, R. O., Friese, M. A. & Gold, S. M., 22.10.2019, In: CELL REP. 29, 4, p. 810-815.e4

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Pregnancy Enables Expansion of Disease-Specific Regulatory T Cells in an Animal Model of Multiple Sclerosis

    Engler, J. B., Heckmann, N. F., Jäger, J., Gold, S. M. & Friese, M. A., 01.10.2019, In: J IMMUNOL. 203, 7, p. 1743-1752 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Neuronal vulnerability and multilineage diversity in multiple sclerosis

    Schirmer, L., Velmeshev, D., Holmqvist, S., Kaufmann, M., Werneburg, S., Jung, D., Vistnes, S., Stockley, J. H., Young, A., Steindel, M., Tung, B., Goyal, N., Bhaduri, A., Mayer, S., Engler, J. B., Bayraktar, O. A., Franklin, R. J. M., Haeussler, M., Reynolds, R., Schafer, D. P., Friese, M. A., Shiow, L. R., Kriegstein, A. R. & Rowitch, D. H., 09.2019, In: NATURE. 573, 7772, p. 75-82 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Bassoon proteinopathy drives neurodegeneration in multiple sclerosis

    Schattling, B., Engler, J. B., Volkmann, C., Rothammer, N., Woo, M. S., Petersen, M., Winkler, I., Kaufmann, M., Rosenkranz, S. C., Fejtova, A., Thomas, U., Bose, A., Bauer, S., Träger, S., Miller, K. K., Brück, W., Duncan, K. E., Salinas, G., Soba, P., Gundelfinger, E. D., Merkler, D. & Friese, M. A., 22.06.2019, In: NAT NEUROSCI. 22, 6, p. 887-896 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Arc/Arg3.1 defines dendritic cells and Langerhans cells with superior migratory ability independent of phenotype and ontogeny in mice

    Tintelnot, J., Ufer, F., Engler, J. B., Winkler, H., Lücke, K., Mittrücker, H-W. & Friese, M. A., 05.2019, In: EUR J IMMUNOL. 49, 5, p. 724-736 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Progesterone modulates the T cell response via glucocorticoid receptor-dependent pathways

    Hierweger, A. M., Engler, J. B., Friese, M. A., Reichardt, H. M., Lydon, J., DeMayo, F., Mittrücker, H-W. & Arck, P. C., 02.2019, In: AM J REPROD IMMUNOL. 81, 2, p. e13084

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. 2018

  26. T Cell Phenotype and T Cell Receptor Repertoire in Patients with Major Depressive Disorder

    Patas, K., Willing, A., Demiralay, C., Engler, J. B., Lupu, A., Ramien, C., Schäfer, T., Gach, C., Stumm, L., Chan, K., Vignali, M., Arck, P. C., Friese, M. A., Pless, O., Wiedemann, K., Agorastos, A. & Gold, S. M., 2018, In: FRONT IMMUNOL. 9, p. 291

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. 2017

  28. Glucocorticoid receptor in T cells mediates protection from autoimmunity in pregnancy

    Engler, J. B., Kursawe, N., Solano, M. E., Patas, K., Wehrmann, S., Heckmann, N., Lühder, F., Reichardt, H. M., Arck, P. C., Gold, S. M. & Friese, M. A., 10.01.2017, In: P NATL ACAD SCI USA. 114, 2, p. E181-E190

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Prenatal Administration of Betamethasone Causes Changes in the T Cell Receptor Repertoire Influencing Development of Autoimmunity

    Gieras, A., Gehbauer, C., Perna-Barrull, D., Engler, J. B., Diepenbruck, I., Glau, L., Joosse, S. A., Kersten, N., Klinge, S., Mittrücker, H-W., Friese, M. A., Vives-Pi, M. & Tolosa, E., 2017, In: FRONT IMMUNOL. 8, p. 1505

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. 2016

  31. Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation

    Ufer, F., Vargas, P., Engler, J. B., Tintelnot, J., Schattling, B., Winkler, H., Bauer, S., Kursawe, N., Willing, A., Keminer, O., Ohana, O., Salinas-Riester, G., Pless, O., Kuhl, D. & Friese, M. A., 23.09.2016, In: SCI IMMUNOL. 1, 3, p. eaaf8665

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Sex effects on inflammatory and neurodegenerative processes in multiple sclerosis

    Ramien, C., Taenzer, A., Lupu, A., Heckmann, N., Engler, J. B., Patas, K., Friese, M. A. & Gold, S. M., 08.2016, In: NEUROSCI BIOBEHAV R. 67, p. 137-46

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. 2015

  34. Multiple sclerosis associated genetic variants of CD226 impair regulatory T cell function

    Piedavent-Salomon, M., Willing, A., Engler, J. B., Steinbach, K., Bauer, S., Eggert, B., Ufer, F., Kursawe, N., Wehrmann, S., Jäger, J., Reinhardt, S. & Friese, M. A., 11.2015, In: BRAIN. 138, Pt 11, p. 3263-74 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. 2013

  36. Pregnancy and multiple sclerosis: feto-maternal immune cross talk and its implications for disease activity

    Patas, K., Engler, J. B., Friese, M. A. & Gold, S. M., 01.03.2013, In: J REPROD IMMUNOL. 97, 1, p. 140-6 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review