Dipl. Hum.-Biol. Dr. rer. nat. ID: 32498
Hermann Clemens Altmeppen
Publications
- 2024
High throughput spatial immune mapping reveals an innate immune scar in post-COVID-19 brains
Schwabenland, M., Hasavci, D., Frase, S., Wolf, K., Deigendesch, N., Buescher, J. M., Mertz, K. D., Ondruschka, B., Altmeppen, H., Matschke, J., Glatzel, M., Frank, S., Thimme, R., Beck, J., Hosp, J. A., Blank, T., Bengsch, B. & Prinz, M., 25.07.2024, In: ACTA NEUROPATHOL. 148, 1, p. 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases
Song, F., Kovac, V., Mohammadi, B., Littau, J. L., Scharfenberg, F., Matamoros Angles, A., Vanni, I., Shafiq, M., Orge, L., Galliciotti, G., Djakkani, S., Linsenmeier, L., Černilec, M., Hartman, K., Jung, S., Tatzelt, J., Neumann, J. E., Damme, M., Tschirner, S. K., Lichtenthaler, S. F., Ricklefs, F. L., Sauvigny, T., Schmitz, M., Zerr, I., Puig, B., Tolosa, E., Ferrer, I., Magnus, T., Rupnik, M. S., Sepulveda-Falla, D., Matschke, J., Šmid, L. M., Bresjanac, M., Andreoletti, O., Krasemann, S., Foliaki, S. T., Nonno, R., Becker-Pauly, C., Monzo, C., Crozet, C., Haigh, C. L., Glatzel, M., Curin Serbec, V. & Altmeppen, H. C., 09.07.2024, In: ACTA NEUROPATHOL. 148, 1, p. 2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo
Gui, Y., Kim, Y., Brenna, S., Wilmes, M., Zaghen, G., Goulbourne, C. N., Kuchenbecker-Pöls, L., Siebels, B., Voß, H., Gocke, A., Schlüter, H., Schweizer, M., Altmeppen, H. C., Magnus, T., Levy, E. & Puig, B., 20.05.2024, In: CELL MOL LIFE SCI. 81, 1, p. 224Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel mouse model for N-terminal truncated Aβ2-x generation through meprin β overexpression in astrocytes
Armbrust, F., Bickenbach, K., Altmeppen, H., Foggetti, A., Winkelmann, A., Wulff, P., Glatzel, M., Pietrzik, C. U. & Becker-Pauly, C., 13.03.2024, In: CELL MOL LIFE SCI. 81, 1, p. 139Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Inducing prion protein shedding as a neuroprotective and regenerative approach in pathological conditions of the brain: from theory to facts
Matamoros Angles, A., Mohammadi, B., Song, F., Shafiq, M., Brenna, S., Puig Martorell, B., Glatzel, M. & Altmeppen, H. C., 09.2023, In: NEURAL REGEN RES. 18, 9, p. 1869-1875 7 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Vagus nerve inflammation contributes to dysautonomia in COVID-19
Woo, M. S., Shafiq, M., Fitzek, A., Dottermusch, M., Altmeppen, H., Mohammadi, B., Mayer, C., Bal, L. C., Raich, L., Matschke, J., Krasemann, S., Pfefferle, S., Brehm, T. T., Lütgehetmann, M., Schädler, J., Addo, M. M., Schulze Zur Wiesch, J., Ondruschka, B., Friese, M. A. & Glatzel, M., 09.2023, In: ACTA NEUROPATHOL. 146, 3, p. 387-394 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Anchorless risk or released benefit? An updated view on the ADAM10-mediated shedding of the prion protein
Mohammadi, B., Song, F., Matamoros-Angles, A., Shafiq, M., Damme, M., Puig, B., Glatzel, M. & Altmeppen, H. C., 04.2023, In: CELL TISSUE RES. 392, 1, p. 215-234 20 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies
Schmitz, M., Candelise, N., Canaslan, S., Altmeppen, H. C., Matschke, J., Glatzel, M., Younas, N., Zafar, S., Hermann, P. & Zerr, I., 14.03.2023, In: TRANSL NEURODEGENER. 12, 1, p. 12Research output: SCORING: Contribution to journal › SCORING: Review article › Research
An optimized western blot assay provides a comprehensive assessment of the physiological endoproteolytic processing of the prion protein
Vanni, I., Iacobone, F., D’agostino, C., Giovannelli, M., Pirisinu, L., Altmeppen, H. C., Castilla, J., Torres, J. M., Agrimi, U. & Nonno, R., 02.2023, In: J BIOL CHEM. 299, 2, p. 102823 102823.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Loss of Homeostatic Microglia Signature in Prion Diseases
Wang, Y., Hartmann, K., Thies, E., Mohammadi, B., Altmeppen, H., Sepulveda-Falla, D., Glatzel, M. & Krasemann, S., 21.09.2022, In: CELLS-BASEL. 11, 19, 2948.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Autosomal dominantly inherited myopathy likely caused by the TNNT1 variant p.(Asp65Ala)
Holling, T., Lisfeld, J., Johannsen, J., Matschke, J., Song, F., Altmeppen, H. C. & Kutsche, K., 09.2022, In: HUM MUTAT. 43, 9, p. 1224-1233 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The prion protein and its ligands: Insights into structure-function relationships
Shafiq, M., Da Vela, S., Amin, L., Younas, N., Harris, D. A., Zerr, I., Altmeppen, H. C., Svergun, D. & Glatzel, M., 06.2022, In: BBA-MOL CELL RES. 1869, 6, 119240.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes
Bub, A., Brenna, S., Alawi, M., Kügler, P., Gui, Y., Kretz, O., Altmeppen, H., Magnus, T. & Puig, B., 31.05.2022, In: CELL MOL LIFE SCI. 79, 6, p. 329 329.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NeuroCOVID: Insights into Neuroinvasion and Pathophysiology
Matschke, J., Krasemann, S., Altmeppen, H., Shafiq, M. & Glatzel, M., 04.2022, In: Clinical and Translational Neuroscience. 6, 2, 10.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease
Marengo, L., Armbrust, F., Schoenherr, C., Storck, S. E., Schmitt, U., Zampar, S., Wirths, O., Altmeppen, H., Glatzel, M., Kaether, C., Weggen, S., Becker-Pauly, C. & Pietrzik, C. U., 02.03.2022, In: CELL MOL LIFE SCI. 79, 3, 168.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Young COVID-19 Patients Show a Higher Degree of Microglial Activation When Compared to Controls
Matschke, J., Lahann, H., Krasemann, S., Altmeppen, H., Pfefferle, S., Galliciotti, G., Fitzek, A., Sperhake, J-P., Ondruschka, B., Busch, M., Rotermund, N., Schulz, K., Lohr, C., Dottermusch, M. & Glatzel, M., 2022, In: FRONT NEUROL. 13, 908081.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies
Linsenmeier, L., Mohammadi, B., Shafiq, M., Frontzek, K., Bär, J., Shrivastava, A. N., Damme, M., Song, F., Schwarz, A., Da Vela, S., Massignan, T., Jung, S., Correia, A., Schmitz, M., Puig, B., Hornemann, S., Zerr, I., Tatzelt, J., Biasini, E., Saftig, P., Schweizer, M., Svergun, D., Amin, L., Mazzola, F., Varani, L., Thapa, S., Gilch, S., Schätzl, H., Harris, D. A., Triller, A., Mikhaylova, M., Aguzzi, A., Altmeppen, H. C. & Glatzel, M., 26.11.2021, In: SCI ADV. 7, 48, p. eabj1826Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
Wenzel, J., Lampe, J., Müller-Fielitz, H., Schuster, R., Zille, M., Müller, K., Krohn, M., Körbelin, J., Zhang, L., Özorhan, Ü., Neve, V., Wagner, J. U. G., Bojkova, D., Shumliakivska, M., Jiang, Y., Fähnrich, A., Ott, F., Sencio, V., Robil, C., Pfefferle, S., Sauve, F., Coêlho, C. F. F., Franz, J., Spiecker, F., Lembrich, B., Binder, S., Feller, N., König, P., Busch, H., Collin, L., Villaseñor, R., Jöhren, O., Altmeppen, H. C., Pasparakis, M., Dimmeler, S., Cinatl, J., Püschel, K., Zelic, M., Ofengeim, D., Stadelmann, C., Trottein, F., Nogueiras, R., Hilgenfeld, R., Glatzel, M., Prevot, V. & Schwaninger, M., 11.2021, In: NAT NEUROSCI. 24, 11, p. 1522-1533 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disordered structure and flexible roles: using the prion protein N1 fragment for neuroprotective and regenerative therapy
Mohammadi, B., Glatzel, M. & Altmeppen, H. C., 07.2021, In: NEURAL REGEN RES. 16, 7, p. 1431-1432Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer's disease
Shafiq, M., Zafar, S., Younas, N., Noor, A., Puig, B., Altmeppen, H. C., Schmitz, M., Matschke, J., Ferrer, I., Glatzel, M. & Zerr, I., 22.02.2021, In: MOL NEURODEGENER. 16, 1, 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Brain-Derived Extracellular Vesicles in Health and Disease: A Methodological Perspective
Brenna, S., Krisp, C., Altmeppen, H. C., Magnus, T. & Puig, B., 29.01.2021, In: INT J MOL SCI. 22, 3, p. 1365Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Pharmacological inactivation of the prion protein by targeting a folding intermediate
Spagnolli, G., Massignan, T., Astolfi, A., Biggi, S., Rigoli, M., Brunelli, P., Libergoli, M., Ianeselli, A., Orioli, S., Boldrini, A., Terruzzi, L., Bonaldo, V., Maietta, G., Lorenzo, N. L., Fernandez, L. C., Codeseira, Y. B., Tosatto, L., Linsenmeier, L., Vignoli, B., Petris, G., Gasparotto, D., Pennuto, M., Guella, G., Canossa, M., Altmeppen, H. C., Lolli, G., Biressi, S., Pastor, M. M., Requena, J. R., Mancini, I., Barreca, M. L., Faccioli, P. & Biasini, E., 12.01.2021, In: COMMUN BIOL. 4, 1, 62.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake
Brenna, S., Altmeppen, H. C., Mohammadi, B., Rissiek, B., Schlink, F., Ludewig, P., Krisp, C., Schlüter, H., Failla, A. V., Schneider, C., Glatzel, M., Puig, B. & Magnus, T., 27.08.2020, In: J EXTRACELL VESICLES. 9, 1, p. 1809065Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prion protein post-translational modifications modulate heparan sulfate binding and limit aggregate size in prion disease
Callender, J. A., Sevillano, A. M., Soldau, K., Kurt, T. D., Schumann, T., Pizzo, D. P., Altmeppen, H., Glatzel, M., Esko, J. D. & Sigurdson, C. J., 08.2020, In: NEUROBIOL DIS. 142, p. 104955Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Show Me Your Friends and I Tell You Who You Are: The Many Facets of Prion Protein in Stroke
Puig, B., Yang, D., Brenna, S., Altmeppen, H. C. & Magnus, T., 02.07.2020, In: CELLS-BASEL. 9, 7Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Influence of Methanol on Prion Reduction during High Temperature and High Pressure Oleochemical Processes
Mohammadi, B., Raudner, R., Shafiq, M., Ahn, E., Altmeppen, H. C. & Glatzel, M., 08.06.2020, In: EUR J LIPID SCI TECH. 122, 9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation
Mohammadi, B., Linsenmeier, L., Shafiq, M., Puig, B., Galliciotti, G., Giudici, C., Willem, M., Eden, T., Koch-Nolte, F., Lin, Y-H., Tatzelt, J., Glatzel, M. & Altmeppen, H. C., 06.2020, In: MOL NEUROBIOL. 57, 6, p. 2812-2829 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease
Sevillano, A. M., Aguilar-Calvo, P., Kurt, T. D., Lawrence, J. A., Soldau, K., Nam, T. H., Schumann, T., Pizzo, D. P., Nyström, S., Choudhury, B., Altmeppen, H., Esko, J. D., Glatzel, M., Nilsson, K. P. R. & Sigurdson, C. J., 02.03.2020, In: J CLIN INVEST. 130, 3, p. 1350-1362 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions
Aguilar-Calvo, P., Sevillano, A. M., Bapat, J., Soldau, K., Sandoval, D. R., Altmeppen, H. C., Linsenmeier, L., Pizzo, D. P., Geschwind, M. D., Sanchez, H., Appleby, B. S., Cohen, M. L., Safar, J. G., Edland, S. D., Glatzel, M., Nilsson, K. P. R., Esko, J. D. & Sigurdson, C. J., 03.2020, In: ACTA NEUROPATHOL. 139, 3, p. 527-546 20 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
The cellular prion protein and its derived fragments in human prion diseases and their role as potential biomarkers
Thüne, K., Schmitz, M., Villar-Piqué, A., Altmeppen, H. C., Schlomm, M., Zafar, S., Glatzel, M., Llorens, F. & Zerr, I., 11.2019, In: EXPERT REV MOL DIAGN. 19, 11, p. 1007-1018 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular Mechanisms of Prion Diseases (2nd Edition)
Altmeppen, H. C., Puig Martorell, B., Krasemann, S. & Glatzel, M., 04.2019, Prions: Current Progress in Advanced Research (2nd Edition). Sakudo, A. & Onodera, T. (eds.). 2 ed. Caister Academic Press, p. 55 - 70 16 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice
Puig, B., Altmeppen, H. C., Linsenmeier, L., Chakroun, K., Wegwitz, F., Piontek, U. K., Tatzelt, J., Bate, C., Magnus, T. & Glatzel, M., 01.2019, In: PLOS PATHOG. 15, 1, p. e1007520Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Muskelin Coordinates PrP Lysosome versus Exosome Targeting and Impacts Prion Disease Progression
Heisler, F. F., Pechmann, Y., Wieser, I., Altmeppen, H. C., Veenendaal, L., Muhia, M., Schweizer, M., Glatzel, M., Krasemann, S. & Kneussel, M., 19.09.2018, In: NEURON. 99, 6, p. 1155-1169.e9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15
Seipold, L., Altmeppen, H., Koudelka, T., Tholey, A., Kasparek, P., Sedlacek, R., Schweizer, M., Bär, J., Mikhaylova, M., Glatzel, M. & Saftig, P., 09.2018, In: CELL MOL LIFE SCI. 75, 17, p. 3251-3267 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Infectious prions do not induce Aβ deposition in an in vivo seeding model
Rasmussen, J., Krasemann, S., Altmeppen, H., Schwarz, P., Schelle, J., Aguzzi, A., Glatzel, M. & Jucker, M., 06.2018, In: ACTA NEUROPATHOL. 135, 6, p. 965-967 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein
Linsenmeier, L., Mohammadi, B., Wetzel, S., Puig, B., Jackson, W. S., Hartmann, A., Uchiyama, K., Sakaguchi, S., Endres, K., Tatzelt, J., Saftig, P., Glatzel, M. & Altmeppen, H. C., 06.04.2018, In: MOL NEURODEGENER. 13, 1, p. 18Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Diverse functions of the prion protein - Does proteolytic processing hold the key?
Linsenmeier, L., Altmeppen, H. C., Wetzel, S., Mohammadi, B., Saftig, P. & Glatzel, M., 11.2017, In: BBA-MOL CELL RES. 1864, 11 Pt B, p. 2128-2137Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Exosomes in Prion Diseases
Hartmann, A., Altmeppen, H. C., Krasemann, S. & Glatzel, M., 2017, Prion Diseases. Liberski, P. (ed.). 1 ed. Humana Press, p. 197-207 11 p. 12. (Neuromethods; vol. 129).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2016
Tetraspanin 3: A central endocytic membrane component regulating the expression of ADAM10, presenilin and the amyloid precursor protein
Seipold, L., Damme, M., Prox, J., Rabe, B., Kasparek, P., Sedlacek, R., Altmeppen, H. C., Willem, M., Boland, B., Glatzel, M. & Saftig, P., 03.11.2016, In: BBA-MOL CELL RES. 1864, 1, p. 217-230Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Misfolding leads the way to unraveling signaling pathways in the pathophysiology of prion diseases
Puig Martorell, B., Altmeppen, H. C. & Glatzel, M., 11.2016, In: PRION. 10, 6, p. 434-443Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity
Falker, C., Hartmann, A., Guett, I., Dohler, F., Altmeppen, H., Betzel, C., Schubert, R., Thurm, D., Wegwitz, F., Joshi, P., Verderio, C., Krasemann, S. & Glatzel, M., 01.04.2016, In: J NEUROCHEM. 137, 1, p. 88-100Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site
Schönherr, C., Bien, J., Isbert, S., Wichert, R., Prox, J., Altmeppen, H., Kumar, S., Walter, J., Lichtenthaler, S. F., Weggen, S., Glatzel, M., Becker-Pauly, C. & Pietrzik, C. U., 19.02.2016, In: MOL NEURODEGENER. 11, 1, p. 19Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice
Puig Martorell, B., Altmeppen, H. C., Ulbrich, S., Linsenmeier, L., Krasemann, S., Chakroun, K., Acevedo-Morantes, C. Y., Wille, H., Tatzelt, J. & Glatzel, M., 2016, In: SCI REP-UK. 6, p. 24970Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
The sheddase ADAM10 is a potent modulator of prion disease
Altmeppen, H. C., Prox, J., Krasemann, S., Puig Martorell, B., Kruszewski, K., Dohler, F., Bernreuther, C., Hoxha, A., Linsenmeier, L., Sikorska, B., Liberski, P. P., Bartsch, U., Saftig, P. & Glatzel, M., 01.01.2015, In: ELIFE. 4Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Shedding light on prion disease
Glatzel, M., Linsenmeier, L., Dohler, F., Krasemann, S., Puig Martorell, B. & Altmeppen, H. C., 2015, In: PRION. 9, 4, p. 244-256Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance
Rothaug, M., Zunke, F., Mazzulli, J. R., Schweizer, M., Altmeppen, H., Lüllmann-Rauch, R., Kallemeijn, W. W., Gaspar, P., Aerts, J. M., Glatzel, M., Saftig, P., Krainc, D., Schwake, M. & Blanz, J., 28.10.2014, In: P NATL ACAD SCI USA. 111, 43, p. 15573-8 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease
Dohler, F., Sepulveda-Falla, D., Krasemann, S., Altmeppen, H., Schlüter, H., Hildebrand, D., Zerr, I., Matschke, J. & Glatzel, M., 01.03.2014, In: BRAIN. 137, Pt 3, p. 873-86 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The GPI-anchoring of PrP: Implications in sorting and pathogenesis
Puig Martorell, B., Altmeppen, H. & Glatzel, M., 01.01.2014, In: PRION. 8, 1, p. 11-18Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Roles of endoproteolytic α-cleavage and shedding of the prion protein in neurodegeneration
Altmeppen, H. C., Prox, J., Puig Martorell, B., Dohler, F., Falker, C., Krasemann, S. & Glatzel, M., 01.09.2013, In: FEBS J. 280, 18, p. 4338-47 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions
Prox, J., Bernreuther, C., Altmeppen, H., Grendel, J., Glatzel, M., D'Hooge, R., Stroobants, S., Ahmed, T., Balschun, D., Willem, M., Lammich, S., Isbrandt, D., Schweizer, M., Horré, K., De Strooper, B. & Saftig, P., 07.08.2013, In: J NEUROSCI. 33, 32, p. 12915-28, 12928aResearch output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review