Research ExplorerScientific StaffAntonio Failla Publications

Dr.rer.nat. ID: 2366847

Antonio Failla

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Affiliations
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Publications

  1. 2024

  2. Adeno-associated virus-based gene therapy treats inflammatory kidney disease in mice

    Wu, G., Liu, S., Hagenstein, J., Alawi, M., Hengel, F. E., Schaper, M., Akyüz, N., Liao, Z., Wanner, N., Tomas, N. M., Failla, A. V., Dierlamm, J., Körbelin, J., Lu, S. & Huber, T. B., 15.08.2024, In: J CLIN INVEST. 134, 17

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans

    Hassani Nia, F., Woike, D., Bento, I., Niebling, S., Tibbe, D., Schulz, K., Hirnet, D., Skiba, M., Hönck, H-H., Veith, K., Günther, C., Scholz, T., Bierhals, T., Driemeyer, J., Bend, R., Failla, A. V., Lohr, C., Alai, M. G. & Kreienkamp, H-J., 06.2024, In: MOL PSYCHIATR. 29, 6, p. 1683-1697 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. 2023

  5. Internally tagged Vps10p-Domain receptors reveal uptake of the neurotrophin BDNF

    Klein, M., Failla, A. V. & Hermey, G., 10.2023, In: J BIOL CHEM. 299, 10, p. 105216

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal

    Grochowska, K. M., Sperveslage, M., Raman, R., Failla, A. V., Głów, D., Schulze, C., Laprell, L., Fehse, B. & Kreutz, M. R., 29.08.2023, In: CELL REP. 42, 8, p. 112998

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Adhesion to laminin-1 and collagen IV induces the formation of Ca2+ microdomains that sensitize mouse T cells for activation

    Weiß, M., Hernandez, L. C., Gil Montoya, D. C., Löhndorf, A., Krüger, A., Kopdag, M., Uebler, L., Landwehr, M., Nawrocki, M., Huber, S., Woelk, L-M., Werner, R., Failla, A. V., Flügel, A., Dupont, G., Guse, A. H. & Diercks, B-P., 20.06.2023, In: SCIENCE SIGNALING. 16, 790, p. eabn9405

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Human platelets release amyloid peptides β1-40 and β1-42 in response to haemostatic, immune, and hypoxic stimuli

    Wolska, N., Celikag, M., Failla, A. V., Tarafdar, A., Renné, T., Torti, M., Canobbio, I. & Pula, G., 05.2023, In: RES PRACT THROMB HAE. 7, 4, 100154.

    Research output: SCORING: Contribution to journal › Short publication › Research › peer-review

  9. Osteocyte apoptosis and cellular micropetrosis signify skeletal aging in type 1 diabetes

    Dragoun Kolibová, S., Wölfel, E. M., Hemmatian, H., Milovanovic, P., Mushumba, H., Wulff, B., Neidhardt, M., Püschel, K., Failla, A. V., Vlug, A., Schlaefer, A., Ondruschka, B., Amling, M., Hofbauer, L. C., Rauner, M., Busse, B. & Jähn-Rickert, K., 05.2023, In: ACTA BIOMATER. 162, p. 254-265 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. MINFLUX imaging of a bacterial molecular machine at nanometer resolution

    Carsten, A., Rudolph, M., Weihs, T., Schmidt, R., Jansen, I., Wurm, C. A., Diepold, A., Failla, A. V., Wolters, M. & Aepfelbacher, M., 01.2023, In: METHODS APPL FLUORES. 11, 1, 015004.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. 2022

  12. Polymerogenic neuroserpin causes mitochondrial alterations and activates NFκB but not the UPR in a neuronal model of neurodegeneration FENIB

    D'Acunto, E., Gianfrancesco, L., Serangeli, I., D'Orsi, M., Sabato, V., Guadagno, N. A., Bhosale, G., Caristi, S., Failla, A. V., De Jaco, A., Cacci, E., Duchen, M. R., Lupo, G., Galliciotti, G. & Miranda, E., 21.07.2022, In: CELL MOL LIFE SCI. 79, 8, p. 437

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Disruption of tubulin-alpha4a polyglutamylation prevents aggregation of hyper-phosphorylated tau and microglia activation in mice

    Hausrat, T. J., Janiesch, P. C., Breiden, P., Lutz, D., Hoffmeister-Ullerich, S., Hermans-Borgmeyer, I., Failla, A. V. & Kneussel, M., 20.07.2022, In: NAT COMMUN. 13, 1, 4192.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Mutations affecting the N-terminal domains of SHANK3 point to different pathomechanisms in neurodevelopmental disorders

    Woike, D., Wang, E., Tibbe, D., Hassani Nia, F., Failla, A. V., Kibæk, M., Overgård, T. M., Larsen, M. J., Fagerberg, C. R., Barsukov, I. & Kreienkamp, H-J., 18.01.2022, In: SCI REP-UK. 12, 1, 902.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Development of an artificial synovial fluid useful for studying Staphylococcus epidermidis joint infections

    Stamm, J., Weißelberg, S., Both, A., Failla, A. V., Nordholt, G., Büttner, H., Linder, S., Aepfelbacher, M. & Rohde, H., 2022, In: FRONT CELL INFECT MI. 12, 948151.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. 2021

  17. Reorganization of the osteocyte lacuno-canalicular network characteristics in tumor sites of an immunocompetent murine model of osteotropic cancers

    Hemmatian, H., Conrad, S., Furesi, G., Mletzko, K., Krug, J., Failla, A. V., Kuhlmann, J. D., Rauner, M., Busse, B. & Jähn-Rickert, K., 11.2021, In: BONE. 152, 116074.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer

    Elazezy, M., Schwentesius, S., Stegat, L., Wikman, H., Werner, S., Mansour, W. Y., Failla, A. V., Peine, S., Müller, V., Thiery, J. P., Ebrahimi Warkiani, M., Pantel, K. & Joosse, S. A., 31.07.2021, In: CANCERS. 13, 15, 3869.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation

    Roggenkamp, H. G., Khansahib, I., Hernandez C, L. C., Zhang, Y., Lodygin, D., Krüger, A., Gu, F., Möckl, F., Löhndorf, A., Wolters, V., Woike, D., Rosche, A., Bauche, A., Schetelig, D., Werner, R., Schlüter, H., Failla, A. V., Meier, C., Fliegert, R., Walseth, T. F., Flügel, A., Diercks, B-P. & Guse, A. H., 23.03.2021, In: SCI SIGNAL. 14, 675

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Distinct clonal lineages and within-host diversification shape invasive Staphylococcus epidermidis populations

    Both, A., Huang, J., Qi, M., Lausmann, C., Weißelberg, S., Büttner, H., Lezius, S., Failla, A. V., Christner, M., Stegger, M., Gehrke, T., Baig, S., Citak, M., Alawi, M., Aepfelbacher, M. & Rohde, H., 02.2021, In: PLOS PATHOG. 17, 2, p. e1009304

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. 2020

  22. Differences of the tumour cell glycocalyx affect binding of capsaicin-loaded chitosan nanocapsules

    von Palubitzki, L., Wang, Y., Hoffmann, S., Vidal-Y-Sy, S., Zobiak, B., Failla, A. V., Schmage, P., John, A., Osorio-Madrazo, A., Bauer, A. T., Schneider, S. W., Goycoolea, F. M. & Gorzelanny, C., 31.12.2020, In: SCI REP-UK. 10, 1, p. 22443

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Glioma escape signature and clonal development under immune pressure

    Maire, C. L., Mohme, M., Bockmayr, M., Fita, K. D., Riecken, K., Börnigen, D., Alawi, M., Failla, A. V., Kolbe, K., Zapf, S., Holz, M., Neumann, K., Dührsen, L., Lange, T., Fehse, B., Westphal, M. & Lamszus, K., 01.10.2020, In: J CLIN INVEST. 130, 10, p. 5257-5271 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake

    Brenna, S., Altmeppen, H. C., Mohammadi, B., Rissiek, B., Schlink, F., Ludewig, P., Krisp, C., Schlüter, H., Failla, A. V., Schneider, C., Glatzel, M., Puig, B. & Magnus, T., 27.08.2020, In: J EXTRACELL VESICLES. 9, 1, p. 1809065

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Evaluation of Microfluidic Ceiling Designs for the Capture of Circulating Tumor Cells on a Microarray Platform

    Liu, H-Y., Koch, C., Haller, A., Joosse, S. A., Kumar, R., Vellekoop, M. J., Horst, L. J., Keller, L., Babayan, A., Failla, A. V., Jensen, J., Peine, S., Keplinger, F., Fuchs, H., Pantel, K. & Hirtz, M., 02.2020, In: ADV BIOSYST. 4, 2, p. e1900162

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Mice lacking plastin-3 display a specific defect of cortical bone acquisition

    Yorgan, T., Sari, H., Rolvien, T., Windhorst, S., Failla, A. V., Kornak, U., Oheim, R., Amling, M. & Schinke, T., 01.2020, In: BONE. 130, p. 115062

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. 2019

  28. SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals

    Andres-Alonso, M., Ammar, M. R., Butnaru, I., Gomes, G. M., Acuña Sanhueza, G., Raman, R., Yuanxiang, P., Borgmeyer, M., Lopez-Rojas, J., Raza, S. A., Brice, N., Hausrat, T. J., Macharadze, T., Diaz-Gonzalez, S., Carlton, M., Failla, A. V., Stork, O., Schweizer, M., Gundelfinger, E. D., Kneussel, M., Spilker, C., Karpova, A. & Kreutz, M. R., 29.11.2019, In: NAT COMMUN. 10, 1, p. 5448

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Thrombospondin Type 1 Domain-Containing 7A Localizes to the Slit Diaphragm and Stabilizes Membrane Dynamics of Fully Differentiated Podocytes

    Herwig, J., Skuza, S., Sachs, W., Sachs, M., Failla, A. V., Rune, G., Meyer, T. N., Fester, L. & Meyer-Schwesinger, C., 05.2019, In: J AM SOC NEPHROL. 30, 5, p. 824-839 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome

    Sharaf, A., Mensching, L., Keller, C., Rading, S., Scheffold, M., Palkowitsch, L., Djogo, N., Rezgaoui, M., Kestler, H. A., Moepps, B., Failla, A. V. & Karsak, M., 2019, In: FRONT MOL NEUROSCI. 12, p. 224

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. 2018

  32. Visualization of translocons in Yersinia type III protein secretion machines during host cell infection

    Nauth, T., Huschka, F., Schweizer, M., Bosse, J. B., Diepold, A., Failla, A. V., Steffen, A., Stradal, T., Wolters, M. & Aepfelbacher, M., 26.12.2018, In: PLOS PATHOG. 14, 12, p. e1007527

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.

    Diercks, B-P., Werner, R., Weidemüller, P., Czarniak, F., Hernandez, L. C., Lehmann, C., Rosche, A., Krüger, A., Kaufmann, U., Vaeth, M., Failla, A., Zobiak, B., Kandil, F-I., Schetelig, D., Ruthenbeck, A., Meier, C., Lodygin, D., Flügel, A., Ren, D., Wolf, I., Feske, S. & Guse, A., 18.12.2018, In: SCIENCE SIGNALING. 11, 561, p. eaat0358

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Trajectory analysis unveils Reelin's role in the directed migration of granule cells in the dentate gyrus

    Wang, S., Brunne, B., Zhao, S., Chai, X., Li, J., Lau, J., Failla, A. V., Zobiak, B., Sibbe, M., Westbrook, G. L., Lutz, D. & Frotscher, M., 03.01.2018, In: J NEUROSCI. 38, 1, p. 137-148 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. 2016

  36. Reelin and cofilin cooperate during the migration of cortical neurons: a quantitative morphological analysis

    Chai, X., Zhao, S., Fan, L., Zhang, W., Lu, X., Shao, H., Wang, S., Song, L., Failla, A. V., Zobiak, B., Mannherz, H. G. & Frotscher, M., 15.03.2016, In: DEVELOPMENT. 143, 6, p. 1029-40 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. 2015

  38. Tight junctions form a barrier in porcine hair follicles

    Mathes, C., Brandner, J. M., Laue, M., Raesch, S. S., Hansen, S., Failla, A. V., Vidal, S., Moll, I., Schaefer, U. F. & Lehr, C-M., 29.12.2015, In: EUR J CELL BIOL. 95, 2, p. 89-99

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion

    Lin, Y-N., Bhuwania, R., Gromova, K., Failla, A. V., Lange, T., Riecken, K., Linder, S., Kneussel, M., Izbicki, J. R. & Windhorst, S., 30.07.2015, In: ONCOTARGET. 6, 21, p. 18577-89 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Ex vivo aorta patch model for analysis of cellular adhesion

    Lin, Y-N., Thata, R. N., Failla, A. V., Geissen, M., Daum, G. & Windhorst, S., 06.2015, In: TISSUE CELL. 47, 3, p. 266-272 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Single gold nanorods as optical probes for spectral imaging

    Wackenhut, F., Failla, A. V. & Meixner, A. J., 05.2015, In: ANAL BIOANAL CHEM. 407, 14, p. 4029-4034 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. The catalytic domain of inositol-1,4,5-trisphosphate 3-kinase-a contributes to ITPKA-induced modulation of F-actin

    Ashour, D. J., Pelka, B., Jaaks, P., Wundenberg, T., Blechner, C., Zobiak, B., Failla, A. V. & Windhorst, S., 02.2015, In: CYTOSKELETON. 72, 2, p. 93-100 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. 2014

  44. Enhanced single-molecule spectroscopy in highly confined optical fields: from λ/2-Fabry-Pérot resonators to plasmonic nano-antennas

    Kern, A. M., Zhang, D., Brecht, M., Chizhik, A. I., Failla, A. V., Wackenhut, F. & Meixner, A. J., 21.02.2014, In: CHEM SENSES. 43, 4, p. 1263-86 24 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. 2013

  46. Sensing dielectric media on the nanoscale with freely oriented gold nanorods

    Wackenhut, F., Failla, A. V. & Meixner, A. J., 21.04.2013, In: PHYS CHEM CHEM PHYS. 15, 15, p. 5407-5414 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. 2001

  48. Spatially modulated illumination microscopy: online visualization of intensity distribution and prediction of nanometer precision of axial distance measurements by computer simulations

    Albrecht, B., Failla, A. V., Heintzmann, R. & Cremer, C., 07.2001, In: J BIOMED OPT. 6, 3, p. 292-299 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review