Vitamin E supplementation and lifespan in model organisms

Insa Wolf; K Pallauf; J K Bendall; L Paulsen; S Nikolai; P Huebbe; T Roeder; G Rimbach

doi:10.1016/j.arr.2012.10.002

Vitamin E supplementation and lifespan in model organisms

Standard

Vitamin E supplementation and lifespan in model organisms. / Wolf, Insa; Pallauf, K; Bendall, J K; Paulsen, L; Nikolai, S; Huebbe, P; Roeder, T; Rimbach, G.

in: AGEING RES REV, Jahrgang 12, Nr. 1, 01.01.2013, S. 365-75.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Wolf, I, Pallauf, K, Bendall, JK, Paulsen, L, Nikolai, S, Huebbe, P, Roeder, T & Rimbach, G 2013, 'Vitamin E supplementation and lifespan in model organisms', AGEING RES REV, Jg. 12, Nr. 1, S. 365-75. https://doi.org/10.1016/j.arr.2012.10.002

APA

Wolf, I., Pallauf, K., Bendall, J. K., Paulsen, L., Nikolai, S., Huebbe, P., Roeder, T., & Rimbach, G. (2013). Vitamin E supplementation and lifespan in model organisms. AGEING RES REV, 12(1), 365-75. https://doi.org/10.1016/j.arr.2012.10.002

Vancouver

Wolf I, Pallauf K, Bendall JK, Paulsen L, Nikolai S, Huebbe P et al. Vitamin E supplementation and lifespan in model organisms. AGEING RES REV. 2013 Jan 1;12(1):365-75. https://doi.org/10.1016/j.arr.2012.10.002

Bibtex

@article{514453c69847436abdfea688b64cb360,

title = "Vitamin E supplementation and lifespan in model organisms",

abstract = "We have conducted a comprehensive literature review regarding the effect of vitamin E on lifespan in model organisms including single-cell organisms, rotifers, Caenorhabditis elegans, Drosophila melanogaster and laboratory rodents. We searched Pubmed and ISI Web of knowledge for studies up to 2011 using the terms {"}tocopherols{"}, {"}tocotrienols{"}, {"}lifespan{"} and {"}longevity{"} in the above mentioned model organisms. Twenty-four studies were included in the final analysis. While some studies suggest an increase in lifespan due to vitamin E, other studies did not observe any vitamin E-mediated changes in lifespan in model organisms. Furthermore there are several studies reporting a decrease in lifespan in response to vitamin E supplementation. Different outcomes between studies may be partly related to species-specific differences, differences in vitamin E concentrations and the vitamin E congeners administered. The findings of our literature review suggest that there is no consistent beneficial effect of vitamin E on lifespan in model organisms which is consistent with reports in human intervention studies.",

keywords = "Animals, Antioxidants, Caenorhabditis elegans, Diptera, Drosophila, Drosophila melanogaster, Humans, Longevity, Mice, Nematoda, Rats, Saccharomyces cerevisiae, Vitamin E",

author = "Insa Wolf and K Pallauf and Bendall, {J K} and L Paulsen and S Nikolai and P Huebbe and T Roeder and G Rimbach",

year = "2013",

month = jan,

day = "1",

doi = "10.1016/j.arr.2012.10.002",

language = "English",

volume = "12",

pages = "365--75",

journal = "AGEING RES REV",

issn = "1568-1637",

publisher = "Elsevier Ireland Ltd",

number = "1",

}

RIS

TY - JOUR

T1 - Vitamin E supplementation and lifespan in model organisms

AU - Wolf, Insa

AU - Pallauf, K

AU - Bendall, J K

AU - Paulsen, L

AU - Nikolai, S

AU - Huebbe, P

AU - Roeder, T

AU - Rimbach, G

PY - 2013/1/1

Y1 - 2013/1/1

N2 - We have conducted a comprehensive literature review regarding the effect of vitamin E on lifespan in model organisms including single-cell organisms, rotifers, Caenorhabditis elegans, Drosophila melanogaster and laboratory rodents. We searched Pubmed and ISI Web of knowledge for studies up to 2011 using the terms "tocopherols", "tocotrienols", "lifespan" and "longevity" in the above mentioned model organisms. Twenty-four studies were included in the final analysis. While some studies suggest an increase in lifespan due to vitamin E, other studies did not observe any vitamin E-mediated changes in lifespan in model organisms. Furthermore there are several studies reporting a decrease in lifespan in response to vitamin E supplementation. Different outcomes between studies may be partly related to species-specific differences, differences in vitamin E concentrations and the vitamin E congeners administered. The findings of our literature review suggest that there is no consistent beneficial effect of vitamin E on lifespan in model organisms which is consistent with reports in human intervention studies.

AB - We have conducted a comprehensive literature review regarding the effect of vitamin E on lifespan in model organisms including single-cell organisms, rotifers, Caenorhabditis elegans, Drosophila melanogaster and laboratory rodents. We searched Pubmed and ISI Web of knowledge for studies up to 2011 using the terms "tocopherols", "tocotrienols", "lifespan" and "longevity" in the above mentioned model organisms. Twenty-four studies were included in the final analysis. While some studies suggest an increase in lifespan due to vitamin E, other studies did not observe any vitamin E-mediated changes in lifespan in model organisms. Furthermore there are several studies reporting a decrease in lifespan in response to vitamin E supplementation. Different outcomes between studies may be partly related to species-specific differences, differences in vitamin E concentrations and the vitamin E congeners administered. The findings of our literature review suggest that there is no consistent beneficial effect of vitamin E on lifespan in model organisms which is consistent with reports in human intervention studies.

KW - Animals

KW - Antioxidants

KW - Caenorhabditis elegans

KW - Diptera

KW - Drosophila

KW - Drosophila melanogaster

KW - Humans

KW - Longevity

KW - Mice

KW - Nematoda

KW - Rats

KW - Saccharomyces cerevisiae

KW - Vitamin E

U2 - 10.1016/j.arr.2012.10.002

DO - 10.1016/j.arr.2012.10.002

M3 - SCORING: Journal article

C2 - 23099151

VL - 12

SP - 365

EP - 375

JO - AGEING RES REV

JF - AGEING RES REV

SN - 1568-1637

IS - 1

ER -