The impact of early perfusion CT measurement after extracranial-intracranial bypass surgery
Standard
The impact of early perfusion CT measurement after extracranial-intracranial bypass surgery : results of a pilot study. / Eicker, Sven O; Beseoglu, Kerim; Etminan, Nima; Turowski, Bernd; Steiger, Hans-Jakob; Hänggi, Daniel.
in: ACTA NEUROCHIR SUPPL, Jahrgang 112, 2011, S. 25-9.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - The impact of early perfusion CT measurement after extracranial-intracranial bypass surgery
T2 - results of a pilot study
AU - Eicker, Sven O
AU - Beseoglu, Kerim
AU - Etminan, Nima
AU - Turowski, Bernd
AU - Steiger, Hans-Jakob
AU - Hänggi, Daniel
PY - 2011
Y1 - 2011
N2 - OBJECTIVE: The early postoperative period after extracranial-intracranial bypass surgery carries the risk of hypo- as well as hyperperfusion. The purpose of this study is to evaluate early perfusion computerized tomography (PCT) after revascularization to assess the hemodynamic balance.METHODS: Standard cerebral bypass surgery was performed on ten patients, and PCT measurement within 6 h after surgery was performed and analyzed.RESULTS: The hemisphere with reduced cerebral vascular reserve (CVR) showed a regional cerebral baseline blood flow (CBF) of 5.58 ± 1.69 and a regional cerebral baseline blood volume (CBV) of 2.41 ± 0.76 before surgery. Mean transit time (MTT) was 4.16 ± 0.9 s and time to peak (TTP) 3.25 ± 1.62 s. After the procedure values changed significantly (p < 0.05) in eight patients who had no complications. Patency rate was documented in all patients by angiography. One patient showed a decrease of CBF and CBV and an increase of MTT and TTP. Clinically the patient developed a transient hemiparesis immediately after surgery. Another patient showed the expected increase in CBF and CBV; however, MTT and TTP also increased. A delayed hemiparesis probably related to hyperperfusion occurred with improvement in the follow-up.CONCLUSION: This pilot study demonstrates that early PCT parameters can provide immediate and detailed information about hemodynamic parameters and seems to have a predictive value regarding the morbidity of hypo- or hyperperfusion in patients after cerebral bypass surgery.
AB - OBJECTIVE: The early postoperative period after extracranial-intracranial bypass surgery carries the risk of hypo- as well as hyperperfusion. The purpose of this study is to evaluate early perfusion computerized tomography (PCT) after revascularization to assess the hemodynamic balance.METHODS: Standard cerebral bypass surgery was performed on ten patients, and PCT measurement within 6 h after surgery was performed and analyzed.RESULTS: The hemisphere with reduced cerebral vascular reserve (CVR) showed a regional cerebral baseline blood flow (CBF) of 5.58 ± 1.69 and a regional cerebral baseline blood volume (CBV) of 2.41 ± 0.76 before surgery. Mean transit time (MTT) was 4.16 ± 0.9 s and time to peak (TTP) 3.25 ± 1.62 s. After the procedure values changed significantly (p < 0.05) in eight patients who had no complications. Patency rate was documented in all patients by angiography. One patient showed a decrease of CBF and CBV and an increase of MTT and TTP. Clinically the patient developed a transient hemiparesis immediately after surgery. Another patient showed the expected increase in CBF and CBV; however, MTT and TTP also increased. A delayed hemiparesis probably related to hyperperfusion occurred with improvement in the follow-up.CONCLUSION: This pilot study demonstrates that early PCT parameters can provide immediate and detailed information about hemodynamic parameters and seems to have a predictive value regarding the morbidity of hypo- or hyperperfusion in patients after cerebral bypass surgery.
KW - Adolescent
KW - Adult
KW - Aged
KW - Carotid Artery Diseases
KW - Cerebral Revascularization
KW - Cerebrovascular Circulation
KW - Female
KW - Follow-Up Studies
KW - Hemodynamics
KW - Humans
KW - Male
KW - Middle Aged
KW - Perfusion
KW - Pilot Projects
KW - Retrospective Studies
KW - Tomography, X-Ray Computed
KW - Treatment Outcome
KW - Young Adult
U2 - 10.1007/978-3-7091-0661-7_5
DO - 10.1007/978-3-7091-0661-7_5
M3 - SCORING: Journal article
C2 - 21691983
VL - 112
SP - 25
EP - 29
JO - ACTA NEUROCHIR SUPPL
JF - ACTA NEUROCHIR SUPPL
SN - 0065-1419
ER -