Standardisierte mikroRNA-Analytik - die große Chance für Biomarkerstudien?
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Standardisierte mikroRNA-Analytik - die große Chance für Biomarkerstudien? / Fauth, Maria; Saul, Meike J.
in: BIOspektrum, Jahrgang 26, 2020, S. 621–623.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › Kurzpublikation › Forschung › Begutachtung
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TY - JOUR
T1 - Standardisierte mikroRNA-Analytik - die große Chance für Biomarkerstudien?
AU - Fauth, Maria
AU - Saul, Meike J
PY - 2020
Y1 - 2020
N2 - Circulating microRNAs (miRs) represent promising diagnostic and prognostic biomarkers for various diseases. Despite the high number of biomarker studies, the results of these studies are hardly reproducible. This makes it difficult to transfer the results into clinical application. In this context, acceptance criteria for the quantification of miRs by reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) may help to standardize miR analysis and improve reproducibility.
AB - Circulating microRNAs (miRs) represent promising diagnostic and prognostic biomarkers for various diseases. Despite the high number of biomarker studies, the results of these studies are hardly reproducible. This makes it difficult to transfer the results into clinical application. In this context, acceptance criteria for the quantification of miRs by reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) may help to standardize miR analysis and improve reproducibility.
U2 - 10.1007/s12268-020-1462-7
DO - 10.1007/s12268-020-1462-7
M3 - Kurzpublikation
VL - 26
SP - 621
EP - 623
JO - BIOspektrum
JF - BIOspektrum
SN - 0947-0867
ER -
