Repetition priming effects dissociate between miniature eye movements and induced gamma-band responses in the human electroencephalogram

TY - JOUR

T1 - Repetition priming effects dissociate between miniature eye movements and induced gamma-band responses in the human electroencephalogram

AU - Hassler, Uwe

AU - Friese, Uwe

AU - Martens, Ulla

AU - Trujillo-Barreto, Nelson

AU - Gruber, Thomas

N1 - © 2013 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

PY - 2013/8/1

Y1 - 2013/8/1

N2 - The role of induced gamma-band responses (iGBRs) in the human electroencephalogram (EEG) is a controversial topic. On the one hand, iGBRs have been associated with neuronal activity reflecting the (re-)activation of cortical object representations. On the other hand, it was shown that miniature saccades (MSs) lead to high-frequency artifacts in the EEG that can mimic cortical iGBRs. We recorded EEG and eye movements simultaneously while participants were engaged in a combined repetition priming and object recognition experiment. MS rates were mainly modulated by object familiarity in a time window from 100 to 300 ms after stimulus onset. In contrast, artifact-corrected iGBRs were sensitive to object repetition and object familiarity in a prolonged time window. EEG source analyses revealed that stimulus repetitions modulated iGBRs in temporal and occipital cortex regions while familiarity was associated with activity in parieto-occipital regions. These results are in line with neuroimaging studies employing functional magnetic resonance imaging or magnetoencephalography. We conclude that MSs reflect early mechanisms of visual perception while iGBRs mirror the activation of cortical networks representing a perceived object.

AB - The role of induced gamma-band responses (iGBRs) in the human electroencephalogram (EEG) is a controversial topic. On the one hand, iGBRs have been associated with neuronal activity reflecting the (re-)activation of cortical object representations. On the other hand, it was shown that miniature saccades (MSs) lead to high-frequency artifacts in the EEG that can mimic cortical iGBRs. We recorded EEG and eye movements simultaneously while participants were engaged in a combined repetition priming and object recognition experiment. MS rates were mainly modulated by object familiarity in a time window from 100 to 300 ms after stimulus onset. In contrast, artifact-corrected iGBRs were sensitive to object repetition and object familiarity in a prolonged time window. EEG source analyses revealed that stimulus repetitions modulated iGBRs in temporal and occipital cortex regions while familiarity was associated with activity in parieto-occipital regions. These results are in line with neuroimaging studies employing functional magnetic resonance imaging or magnetoencephalography. We conclude that MSs reflect early mechanisms of visual perception while iGBRs mirror the activation of cortical networks representing a perceived object.

KW - Adult

KW - Brain Waves

KW - Cerebral Cortex

KW - Electroencephalography

KW - Eye Movements

KW - Female

KW - Humans

KW - Male

KW - Repetition Priming

KW - Young Adult

U2 - 10.1111/ejn.12244

DO - 10.1111/ejn.12244

M3 - SCORING: Journal article

C2 - 23675819

VL - 38

SP - 2425

EP - 2433

JO - EUR J NEUROSCI

JF - EUR J NEUROSCI

SN - 0953-816X

IS - 3

ER -