Physical examination, central venous pressure, and chest radiography for the prediction of transpulmonary thermodilution-derived hemodynamic parameters in critically ill patients: a prospective trial

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Physical examination, central venous pressure, and chest radiography for the prediction of transpulmonary thermodilution-derived hemodynamic parameters in critically ill patients: a prospective trial. / Saugel, Bernd; Ringmaier, Stephan; Holzapfel, Konstantin; Schuster, Tibor; Phillip, Veit; Schmid, Roland M; Huber, Wolfgang.

in: J CRIT CARE, Jahrgang 26, Nr. 4, 01.08.2011, S. 402-10.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{5fc9a5c9059e46de82cf98a5003538f0,
title = "Physical examination, central venous pressure, and chest radiography for the prediction of transpulmonary thermodilution-derived hemodynamic parameters in critically ill patients: a prospective trial",
abstract = "PURPOSE: Physical examination, assessment of central venous pressure (CVP) and chest radiography are diagnostic tools for estimation of volume status in intensive care unit (ICU) patients. Passive leg raising (PLR) is a test to estimate fluid responsiveness. Transpulmonary thermodilution (TPTD) is established for measurement of cardiac index (CI), global end-diastolic volume index (GEDVI), and extravascular lung water index (EVLWI). This study compares the estimation of volume status using physical examination, CVP, chest radiography, PLR, and TPTD.MATERIALS AND METHODS: This study was a prospective trial. Seventy-one patients in a medical ICU were studied. Interventions were as follows: physical examination by 2 independent examiners. CVP was measured. TPTD was performed. In 2 patient subgroups PLR and chest radiography was performed. Comparison of clinical and x-ray-based estimation of volume status, CVP, PLR, and TPTD variables was performed.RESULTS: Estimation of volume status based on physical examination showed a poor interobserver agreement between the examiners. There was no significant correlation between physical examination-based estimation of volume status and CVP or TPTD-derived GEDVI. There was no significant correlation between CVP and GEDVI, EVLWI or CI. PLR did not indicate fluid responsiveness. Radiographically estimated and TPTD-GEDVI/EVLWI values were significantly different.CONCLUSIONS: In ICU patients, assessment of volume status remains difficult. Physical examination, CVP, and portable radiography do not correlate with TPTD assessment of volume status, preload, or pulmonary hydration.",
keywords = "Central Venous Pressure, Critical Illness, Female, Hemodynamics, Humans, Intensive Care Units, Male, Middle Aged, Physical Examination, Predictive Value of Tests, Prospective Studies, Radiography, Thoracic, Sensitivity and Specificity, Statistics, Nonparametric, Thermodilution",
author = "Bernd Saugel and Stephan Ringmaier and Konstantin Holzapfel and Tibor Schuster and Veit Phillip and Schmid, {Roland M} and Wolfgang Huber",
note = "Copyright {\textcopyright} 2011 Elsevier Inc. All rights reserved.",
year = "2011",
month = aug,
day = "1",
doi = "10.1016/j.jcrc.2010.11.001",
language = "English",
volume = "26",
pages = "402--10",
journal = "J CRIT CARE",
issn = "0883-9441",
publisher = "Elsevier BV",
number = "4",

}

RIS

TY - JOUR

T1 - Physical examination, central venous pressure, and chest radiography for the prediction of transpulmonary thermodilution-derived hemodynamic parameters in critically ill patients: a prospective trial

AU - Saugel, Bernd

AU - Ringmaier, Stephan

AU - Holzapfel, Konstantin

AU - Schuster, Tibor

AU - Phillip, Veit

AU - Schmid, Roland M

AU - Huber, Wolfgang

N1 - Copyright © 2011 Elsevier Inc. All rights reserved.

PY - 2011/8/1

Y1 - 2011/8/1

N2 - PURPOSE: Physical examination, assessment of central venous pressure (CVP) and chest radiography are diagnostic tools for estimation of volume status in intensive care unit (ICU) patients. Passive leg raising (PLR) is a test to estimate fluid responsiveness. Transpulmonary thermodilution (TPTD) is established for measurement of cardiac index (CI), global end-diastolic volume index (GEDVI), and extravascular lung water index (EVLWI). This study compares the estimation of volume status using physical examination, CVP, chest radiography, PLR, and TPTD.MATERIALS AND METHODS: This study was a prospective trial. Seventy-one patients in a medical ICU were studied. Interventions were as follows: physical examination by 2 independent examiners. CVP was measured. TPTD was performed. In 2 patient subgroups PLR and chest radiography was performed. Comparison of clinical and x-ray-based estimation of volume status, CVP, PLR, and TPTD variables was performed.RESULTS: Estimation of volume status based on physical examination showed a poor interobserver agreement between the examiners. There was no significant correlation between physical examination-based estimation of volume status and CVP or TPTD-derived GEDVI. There was no significant correlation between CVP and GEDVI, EVLWI or CI. PLR did not indicate fluid responsiveness. Radiographically estimated and TPTD-GEDVI/EVLWI values were significantly different.CONCLUSIONS: In ICU patients, assessment of volume status remains difficult. Physical examination, CVP, and portable radiography do not correlate with TPTD assessment of volume status, preload, or pulmonary hydration.

AB - PURPOSE: Physical examination, assessment of central venous pressure (CVP) and chest radiography are diagnostic tools for estimation of volume status in intensive care unit (ICU) patients. Passive leg raising (PLR) is a test to estimate fluid responsiveness. Transpulmonary thermodilution (TPTD) is established for measurement of cardiac index (CI), global end-diastolic volume index (GEDVI), and extravascular lung water index (EVLWI). This study compares the estimation of volume status using physical examination, CVP, chest radiography, PLR, and TPTD.MATERIALS AND METHODS: This study was a prospective trial. Seventy-one patients in a medical ICU were studied. Interventions were as follows: physical examination by 2 independent examiners. CVP was measured. TPTD was performed. In 2 patient subgroups PLR and chest radiography was performed. Comparison of clinical and x-ray-based estimation of volume status, CVP, PLR, and TPTD variables was performed.RESULTS: Estimation of volume status based on physical examination showed a poor interobserver agreement between the examiners. There was no significant correlation between physical examination-based estimation of volume status and CVP or TPTD-derived GEDVI. There was no significant correlation between CVP and GEDVI, EVLWI or CI. PLR did not indicate fluid responsiveness. Radiographically estimated and TPTD-GEDVI/EVLWI values were significantly different.CONCLUSIONS: In ICU patients, assessment of volume status remains difficult. Physical examination, CVP, and portable radiography do not correlate with TPTD assessment of volume status, preload, or pulmonary hydration.

KW - Central Venous Pressure

KW - Critical Illness

KW - Female

KW - Hemodynamics

KW - Humans

KW - Intensive Care Units

KW - Male

KW - Middle Aged

KW - Physical Examination

KW - Predictive Value of Tests

KW - Prospective Studies

KW - Radiography, Thoracic

KW - Sensitivity and Specificity

KW - Statistics, Nonparametric

KW - Thermodilution

U2 - 10.1016/j.jcrc.2010.11.001

DO - 10.1016/j.jcrc.2010.11.001

M3 - SCORING: Journal article

C2 - 21273034

VL - 26

SP - 402

EP - 410

JO - J CRIT CARE

JF - J CRIT CARE

SN - 0883-9441

IS - 4

ER -