Physical examination, central venous pressure, and chest radiography for the prediction of transpulmonary thermodilution-derived hemodynamic parameters in critically ill patients: a prospective trial
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Physical examination, central venous pressure, and chest radiography for the prediction of transpulmonary thermodilution-derived hemodynamic parameters in critically ill patients: a prospective trial. / Saugel, Bernd; Ringmaier, Stephan; Holzapfel, Konstantin; Schuster, Tibor; Phillip, Veit; Schmid, Roland M; Huber, Wolfgang.
in: J CRIT CARE, Jahrgang 26, Nr. 4, 01.08.2011, S. 402-10.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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T1 - Physical examination, central venous pressure, and chest radiography for the prediction of transpulmonary thermodilution-derived hemodynamic parameters in critically ill patients: a prospective trial
AU - Saugel, Bernd
AU - Ringmaier, Stephan
AU - Holzapfel, Konstantin
AU - Schuster, Tibor
AU - Phillip, Veit
AU - Schmid, Roland M
AU - Huber, Wolfgang
N1 - Copyright © 2011 Elsevier Inc. All rights reserved.
PY - 2011/8/1
Y1 - 2011/8/1
N2 - PURPOSE: Physical examination, assessment of central venous pressure (CVP) and chest radiography are diagnostic tools for estimation of volume status in intensive care unit (ICU) patients. Passive leg raising (PLR) is a test to estimate fluid responsiveness. Transpulmonary thermodilution (TPTD) is established for measurement of cardiac index (CI), global end-diastolic volume index (GEDVI), and extravascular lung water index (EVLWI). This study compares the estimation of volume status using physical examination, CVP, chest radiography, PLR, and TPTD.MATERIALS AND METHODS: This study was a prospective trial. Seventy-one patients in a medical ICU were studied. Interventions were as follows: physical examination by 2 independent examiners. CVP was measured. TPTD was performed. In 2 patient subgroups PLR and chest radiography was performed. Comparison of clinical and x-ray-based estimation of volume status, CVP, PLR, and TPTD variables was performed.RESULTS: Estimation of volume status based on physical examination showed a poor interobserver agreement between the examiners. There was no significant correlation between physical examination-based estimation of volume status and CVP or TPTD-derived GEDVI. There was no significant correlation between CVP and GEDVI, EVLWI or CI. PLR did not indicate fluid responsiveness. Radiographically estimated and TPTD-GEDVI/EVLWI values were significantly different.CONCLUSIONS: In ICU patients, assessment of volume status remains difficult. Physical examination, CVP, and portable radiography do not correlate with TPTD assessment of volume status, preload, or pulmonary hydration.
AB - PURPOSE: Physical examination, assessment of central venous pressure (CVP) and chest radiography are diagnostic tools for estimation of volume status in intensive care unit (ICU) patients. Passive leg raising (PLR) is a test to estimate fluid responsiveness. Transpulmonary thermodilution (TPTD) is established for measurement of cardiac index (CI), global end-diastolic volume index (GEDVI), and extravascular lung water index (EVLWI). This study compares the estimation of volume status using physical examination, CVP, chest radiography, PLR, and TPTD.MATERIALS AND METHODS: This study was a prospective trial. Seventy-one patients in a medical ICU were studied. Interventions were as follows: physical examination by 2 independent examiners. CVP was measured. TPTD was performed. In 2 patient subgroups PLR and chest radiography was performed. Comparison of clinical and x-ray-based estimation of volume status, CVP, PLR, and TPTD variables was performed.RESULTS: Estimation of volume status based on physical examination showed a poor interobserver agreement between the examiners. There was no significant correlation between physical examination-based estimation of volume status and CVP or TPTD-derived GEDVI. There was no significant correlation between CVP and GEDVI, EVLWI or CI. PLR did not indicate fluid responsiveness. Radiographically estimated and TPTD-GEDVI/EVLWI values were significantly different.CONCLUSIONS: In ICU patients, assessment of volume status remains difficult. Physical examination, CVP, and portable radiography do not correlate with TPTD assessment of volume status, preload, or pulmonary hydration.
KW - Central Venous Pressure
KW - Critical Illness
KW - Female
KW - Hemodynamics
KW - Humans
KW - Intensive Care Units
KW - Male
KW - Middle Aged
KW - Physical Examination
KW - Predictive Value of Tests
KW - Prospective Studies
KW - Radiography, Thoracic
KW - Sensitivity and Specificity
KW - Statistics, Nonparametric
KW - Thermodilution
U2 - 10.1016/j.jcrc.2010.11.001
DO - 10.1016/j.jcrc.2010.11.001
M3 - SCORING: Journal article
C2 - 21273034
VL - 26
SP - 402
EP - 410
JO - J CRIT CARE
JF - J CRIT CARE
SN - 0883-9441
IS - 4
ER -