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Long-term follow-up in patients with presumptive Brugada syndrome treated with implanted defibrillators

Standard

Long-term follow-up in patients with presumptive Brugada syndrome treated with implanted defibrillators. / Steven, Daniel; Roberts-Thomson, Kurt C; Inada, Keiichi; Seiler, Jens; Koplan, Bruce A; Tedrow, Usha B; Sweeney, Michel O; Epstein, Laurence E; Stevenson, William G.

in: J CARDIOVASC ELECTR, Jahrgang 22, Nr. 10, 10.2011, S. 1115-1119.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Steven, D, Roberts-Thomson, KC, Inada, K, Seiler, J, Koplan, BA, Tedrow, UB, Sweeney, MO, Epstein, LE & Stevenson, WG 2011, 'Long-term follow-up in patients with presumptive Brugada syndrome treated with implanted defibrillators', J CARDIOVASC ELECTR, Jg. 22, Nr. 10, S. 1115-1119. https://doi.org/10.1111/j.1540-8167.2011.02075.x

APA

Steven, D., Roberts-Thomson, K. C., Inada, K., Seiler, J., Koplan, B. A., Tedrow, U. B., Sweeney, M. O., Epstein, L. E., & Stevenson, W. G. (2011). Long-term follow-up in patients with presumptive Brugada syndrome treated with implanted defibrillators. J CARDIOVASC ELECTR, 22(10), 1115-1119. https://doi.org/10.1111/j.1540-8167.2011.02075.x

Vancouver

Steven D, Roberts-Thomson KC, Inada K, Seiler J, Koplan BA, Tedrow UB et al. Long-term follow-up in patients with presumptive Brugada syndrome treated with implanted defibrillators. J CARDIOVASC ELECTR. 2011 Okt;22(10):1115-1119. https://doi.org/10.1111/j.1540-8167.2011.02075.x

Bibtex

@article{655f60777b6745659b6aea319c6da887,
title = "Long-term follow-up in patients with presumptive Brugada syndrome treated with implanted defibrillators",
abstract = "INTRODUCTION: Risk stratification for patients with suspected Brugada syndrome (BS) remains difficult. Implantation of cardioverter-defibrillators (ICDs) in high-risk patients provides continuous long-term arrhythmia protection.METHODS: Data of 33 consecutive patients undergoing ICD implantation after BS evaluation between 1995 and 2008 were reviewed.RESULTS: There were 30 (91%) men and 3 (9%) women (46.4 ± 11.7 years). Type I Brugada was noted in 18 (54.5%), type II in 12 (36.4%) patients, and ST elevation after drug challenge in 3 patients (9.1%). Three patients had prior cardiac arrest; 70% a history of syncope; and 56% ventricular arrhythmias at the electrophysiology study. During 7.9 ± 3.6 years of follow-up, 2 patients with prior arrest received appropriate ICD shocks. None of the 30 patients without prior arrest had a sustained arrhythmia detected. ICD-related adverse effects occurred in 11 (33%) patients, including inappropriate shocks in 5 (15%). Eight patients (24%) developed 11 major device-related complications including subclavian vein thrombosis (1), pericardial effusion (1), lead fracture (2), and infection (2); in 4 patients the only complication was premature battery depletion that required early ICD replacement; however, some of these complications such as lead fractures and early battery depletion may not be specific for this patient cohort and may not repeat in the future.CONCLUSION: Risk stratification for patients with BS for primary prevention remains challenging. The low risk of arrhythmic events that is exceeded by ICD-related adverse effects should inform discussions with patients who do not have a prior history of cardiac arrest.",
keywords = "Adult, Boston, Brugada Syndrome/complications, Death, Sudden, Cardiac/etiology, Defibrillators, Implantable/adverse effects, Electric Countershock/adverse effects, Electrocardiography, Electrophysiologic Techniques, Cardiac, Female, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Patient Selection, Prosthesis Failure, Retrospective Studies, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome",
author = "Daniel Steven and Roberts-Thomson, {Kurt C} and Keiichi Inada and Jens Seiler and Koplan, {Bruce A} and Tedrow, {Usha B} and Sweeney, {Michel O} and Epstein, {Laurence E} and Stevenson, {William G}",
note = "{\textcopyright} 2011 Wiley Periodicals, Inc.",
year = "2011",
month = oct,
doi = "10.1111/j.1540-8167.2011.02075.x",
language = "English",
volume = "22",
pages = "1115--1119",
journal = "J CARDIOVASC ELECTR",
issn = "1045-3873",
publisher = "Wiley-Blackwell",
number = "10",

}

RIS

TY - JOUR

T1 - Long-term follow-up in patients with presumptive Brugada syndrome treated with implanted defibrillators

AU - Steven, Daniel

AU - Roberts-Thomson, Kurt C

AU - Inada, Keiichi

AU - Seiler, Jens

AU - Koplan, Bruce A

AU - Tedrow, Usha B

AU - Sweeney, Michel O

AU - Epstein, Laurence E

AU - Stevenson, William G

N1 - © 2011 Wiley Periodicals, Inc.

PY - 2011/10

Y1 - 2011/10

N2 - INTRODUCTION: Risk stratification for patients with suspected Brugada syndrome (BS) remains difficult. Implantation of cardioverter-defibrillators (ICDs) in high-risk patients provides continuous long-term arrhythmia protection.METHODS: Data of 33 consecutive patients undergoing ICD implantation after BS evaluation between 1995 and 2008 were reviewed.RESULTS: There were 30 (91%) men and 3 (9%) women (46.4 ± 11.7 years). Type I Brugada was noted in 18 (54.5%), type II in 12 (36.4%) patients, and ST elevation after drug challenge in 3 patients (9.1%). Three patients had prior cardiac arrest; 70% a history of syncope; and 56% ventricular arrhythmias at the electrophysiology study. During 7.9 ± 3.6 years of follow-up, 2 patients with prior arrest received appropriate ICD shocks. None of the 30 patients without prior arrest had a sustained arrhythmia detected. ICD-related adverse effects occurred in 11 (33%) patients, including inappropriate shocks in 5 (15%). Eight patients (24%) developed 11 major device-related complications including subclavian vein thrombosis (1), pericardial effusion (1), lead fracture (2), and infection (2); in 4 patients the only complication was premature battery depletion that required early ICD replacement; however, some of these complications such as lead fractures and early battery depletion may not be specific for this patient cohort and may not repeat in the future.CONCLUSION: Risk stratification for patients with BS for primary prevention remains challenging. The low risk of arrhythmic events that is exceeded by ICD-related adverse effects should inform discussions with patients who do not have a prior history of cardiac arrest.

AB - INTRODUCTION: Risk stratification for patients with suspected Brugada syndrome (BS) remains difficult. Implantation of cardioverter-defibrillators (ICDs) in high-risk patients provides continuous long-term arrhythmia protection.METHODS: Data of 33 consecutive patients undergoing ICD implantation after BS evaluation between 1995 and 2008 were reviewed.RESULTS: There were 30 (91%) men and 3 (9%) women (46.4 ± 11.7 years). Type I Brugada was noted in 18 (54.5%), type II in 12 (36.4%) patients, and ST elevation after drug challenge in 3 patients (9.1%). Three patients had prior cardiac arrest; 70% a history of syncope; and 56% ventricular arrhythmias at the electrophysiology study. During 7.9 ± 3.6 years of follow-up, 2 patients with prior arrest received appropriate ICD shocks. None of the 30 patients without prior arrest had a sustained arrhythmia detected. ICD-related adverse effects occurred in 11 (33%) patients, including inappropriate shocks in 5 (15%). Eight patients (24%) developed 11 major device-related complications including subclavian vein thrombosis (1), pericardial effusion (1), lead fracture (2), and infection (2); in 4 patients the only complication was premature battery depletion that required early ICD replacement; however, some of these complications such as lead fractures and early battery depletion may not be specific for this patient cohort and may not repeat in the future.CONCLUSION: Risk stratification for patients with BS for primary prevention remains challenging. The low risk of arrhythmic events that is exceeded by ICD-related adverse effects should inform discussions with patients who do not have a prior history of cardiac arrest.

KW - Adult

KW - Boston

KW - Brugada Syndrome/complications

KW - Death, Sudden, Cardiac/etiology

KW - Defibrillators, Implantable/adverse effects

KW - Electric Countershock/adverse effects

KW - Electrocardiography

KW - Electrophysiologic Techniques, Cardiac

KW - Female

KW - Humans

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Patient Selection

KW - Prosthesis Failure

KW - Retrospective Studies

KW - Risk Assessment

KW - Risk Factors

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1111/j.1540-8167.2011.02075.x

DO - 10.1111/j.1540-8167.2011.02075.x

M3 - SCORING: Journal article

C2 - 21545364

VL - 22

SP - 1115

EP - 1119

JO - J CARDIOVASC ELECTR

JF - J CARDIOVASC ELECTR

SN - 1045-3873

IS - 10

ER -