Intensity and inhalation of smoking in the aetiology of laryngeal cancer
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Intensity and inhalation of smoking in the aetiology of laryngeal cancer. / Ramroth, Heribert; Dietz, Andreas; Becher, Heiko.
in: INT J ENV RES PUB HE, Jahrgang 8, Nr. 4, 01.04.2011, S. 976-84.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Intensity and inhalation of smoking in the aetiology of laryngeal cancer
AU - Ramroth, Heribert
AU - Dietz, Andreas
AU - Becher, Heiko
PY - 2011/4/1
Y1 - 2011/4/1
N2 - The carcinogenic effect of smoking on laryngeal cancer is well established; however, the risk pattern for detailed smoking characteristics is less clear. Thus, the aim of this analysis was to quantify the impact of different inhalation behaviours on the risk of laryngeal cancer. We conducted a population-based case control study in Germany, frequency-matched for sex and age, using a standardized questionnaire covering lifelong smoking details, including age at start, time since quitting, types of smoking products, duration, intensity and inhalation behaviour. We found higher risks for increasing duration and intensity of smoking. A clear dose-response relationship was found in all inhalation subgroups, i.e., not only for deep inhalers, but also for those puffing on a cigarette. Clearly reduced risks could be observed for quitting smoking. Changing inhalation habits might be considered as a first step to reducing the risk of developing laryngeal cancer. However, the best way to effectively reduce laryngeal cancer risk is to quit smoking.
AB - The carcinogenic effect of smoking on laryngeal cancer is well established; however, the risk pattern for detailed smoking characteristics is less clear. Thus, the aim of this analysis was to quantify the impact of different inhalation behaviours on the risk of laryngeal cancer. We conducted a population-based case control study in Germany, frequency-matched for sex and age, using a standardized questionnaire covering lifelong smoking details, including age at start, time since quitting, types of smoking products, duration, intensity and inhalation behaviour. We found higher risks for increasing duration and intensity of smoking. A clear dose-response relationship was found in all inhalation subgroups, i.e., not only for deep inhalers, but also for those puffing on a cigarette. Clearly reduced risks could be observed for quitting smoking. Changing inhalation habits might be considered as a first step to reducing the risk of developing laryngeal cancer. However, the best way to effectively reduce laryngeal cancer risk is to quit smoking.
KW - Aged
KW - Alcohol Drinking
KW - Case-Control Studies
KW - Female
KW - Germany
KW - Humans
KW - Inhalation
KW - Laryngeal Neoplasms
KW - Male
KW - Middle Aged
KW - Risk Factors
KW - Smoking
U2 - 10.3390/ijerph8040976
DO - 10.3390/ijerph8040976
M3 - SCORING: Journal article
C2 - 21695025
VL - 8
SP - 976
EP - 984
JO - INT J ENV RES PUB HE
JF - INT J ENV RES PUB HE
SN - 1660-4601
IS - 4
ER -