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IgG4 antibodies and cancer-associated inflammation

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IgG4 antibodies and cancer-associated inflammation : Insights into a novel mechanism of immune escape. / Karagiannis, Panagiotis; Gilbert, Amy E; Nestle, Frank O; Karagiannis, Sophia N.

in: ONCOIMMUNOLOGY, Jahrgang 2, Nr. 7, 01.07.2013, S. e24889.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Karagiannis, P, Gilbert, AE, Nestle, FO & Karagiannis, SN 2013, 'IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escape', ONCOIMMUNOLOGY, Jg. 2, Nr. 7, S. e24889. https://doi.org/10.4161/onci.24889

APA

Karagiannis, P., Gilbert, A. E., Nestle, F. O., & Karagiannis, S. N. (2013). IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escape. ONCOIMMUNOLOGY, 2(7), e24889. https://doi.org/10.4161/onci.24889

Vancouver

Karagiannis P, Gilbert AE, Nestle FO, Karagiannis SN. IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escape. ONCOIMMUNOLOGY. 2013 Jul 1;2(7):e24889. https://doi.org/10.4161/onci.24889

Bibtex

@article{559862fefa184d4b802114048c102157,
title = "IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escape",
abstract = "The role of B cells and antibodies in cancer is insufficiently understood but is receiving increasing attention. We have recently identified IgG4 as an antibody subclass elicited by melanoma-associated interleukin-10-driven inflammation. In this setting, IgG4 exhibit inefficient immunostimulatory capacity and block the cytotoxic activities of other antibodies. These previously unappreciated mechanisms of immune escape may constitute promising targets for the development of novel anticancer immunotherapies.",
author = "Panagiotis Karagiannis and Gilbert, {Amy E} and Nestle, {Frank O} and Karagiannis, {Sophia N}",
year = "2013",
month = jul,
day = "1",
doi = "10.4161/onci.24889",
language = "English",
volume = "2",
pages = "e24889",
journal = "ONCOIMMUNOLOGY",
issn = "2162-402X",
publisher = "Taylor & Francis",
number = "7",

}

RIS

TY - JOUR

T1 - IgG4 antibodies and cancer-associated inflammation

T2 - Insights into a novel mechanism of immune escape

AU - Karagiannis, Panagiotis

AU - Gilbert, Amy E

AU - Nestle, Frank O

AU - Karagiannis, Sophia N

PY - 2013/7/1

Y1 - 2013/7/1

N2 - The role of B cells and antibodies in cancer is insufficiently understood but is receiving increasing attention. We have recently identified IgG4 as an antibody subclass elicited by melanoma-associated interleukin-10-driven inflammation. In this setting, IgG4 exhibit inefficient immunostimulatory capacity and block the cytotoxic activities of other antibodies. These previously unappreciated mechanisms of immune escape may constitute promising targets for the development of novel anticancer immunotherapies.

AB - The role of B cells and antibodies in cancer is insufficiently understood but is receiving increasing attention. We have recently identified IgG4 as an antibody subclass elicited by melanoma-associated interleukin-10-driven inflammation. In this setting, IgG4 exhibit inefficient immunostimulatory capacity and block the cytotoxic activities of other antibodies. These previously unappreciated mechanisms of immune escape may constitute promising targets for the development of novel anticancer immunotherapies.

U2 - 10.4161/onci.24889

DO - 10.4161/onci.24889

M3 - SCORING: Journal article

C2 - 24073371

VL - 2

SP - e24889

JO - ONCOIMMUNOLOGY

JF - ONCOIMMUNOLOGY

SN - 2162-402X

IS - 7

ER -