Flavopiridol protects against inflammation by attenuating leukocyte-endothelial interaction via inhibition of cyclin-dependent kinase 9.
Standard
Flavopiridol protects against inflammation by attenuating leukocyte-endothelial interaction via inhibition of cyclin-dependent kinase 9. / Schmerwitz, Ulrike K; Sass, Gabriele; Khandoga, Alexander G; Joore, Jos; Mayer, Bettina A; Berberich, Nina; Totzke, Frank; Krombach, Fritz; Tiegs, Gisa; Zahler, Stefan; Vollmar, Angelika M; Fürst, Robert.
in: ARTERIOSCL THROM VAS, Jahrgang 31, Nr. 2, 2, 2011, S. 280-288.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Flavopiridol protects against inflammation by attenuating leukocyte-endothelial interaction via inhibition of cyclin-dependent kinase 9.
AU - Schmerwitz, Ulrike K
AU - Sass, Gabriele
AU - Khandoga, Alexander G
AU - Joore, Jos
AU - Mayer, Bettina A
AU - Berberich, Nina
AU - Totzke, Frank
AU - Krombach, Fritz
AU - Tiegs, Gisa
AU - Zahler, Stefan
AU - Vollmar, Angelika M
AU - Fürst, Robert
PY - 2011
Y1 - 2011
N2 - The cyclin-dependent kinase (CDK) inhibitor flavopiridol is currently being tested in clinical trials as anticancer drug. Beyond its cell death-inducing action, we hypothesized that flavopiridol affects inflammatory processes. Therefore, we elucidated the action of flavopiridol on leukocyte-endothelial cell interaction and endothelial activation in vivo and in vitro and studied the underlying molecular mechanisms.
AB - The cyclin-dependent kinase (CDK) inhibitor flavopiridol is currently being tested in clinical trials as anticancer drug. Beyond its cell death-inducing action, we hypothesized that flavopiridol affects inflammatory processes. Therefore, we elucidated the action of flavopiridol on leukocyte-endothelial cell interaction and endothelial activation in vivo and in vitro and studied the underlying molecular mechanisms.
M3 - SCORING: Zeitschriftenaufsatz
VL - 31
SP - 280
EP - 288
JO - ARTERIOSCL THROM VAS
JF - ARTERIOSCL THROM VAS
SN - 1079-5642
IS - 2
M1 - 2
ER -