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Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

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Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. / Lai, Albert; Kharbanda, Samir; Pope, Whitney B; Tran, Anh; Solis, Orestes E; Peale, Franklin; Forrest, William F; Pujara, Kanan; Carrillo, Jose A; Pandita, Ajay; Ellingson, Benjamin M; Bowers, Chauncey W; Soriano, Robert H; Schmidt, Nils-Ole; Mohan, Sankar; Yong, William H; Seshagiri, Somasekar; Modrusan, Zora; Jiang, Zhaoshi; Aldape, Kenneth D; Mischel, Paul S; Liau, Linda M; Escovedo, Cameron J; Chen, Weidong; Nghiemphu, Phioanh Leia; James, C David; Prados, Michael D; Westphal, Manfred; Lamszus, Katrin; Cloughesy, Timothy; Phillips, Heidi S.

in: J CLIN ONCOL, Jahrgang 29, Nr. 34, 34, 2011, S. 4482-4490.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Lai, A, Kharbanda, S, Pope, WB, Tran, A, Solis, OE, Peale, F, Forrest, WF, Pujara, K, Carrillo, JA, Pandita, A, Ellingson, BM, Bowers, CW, Soriano, RH, Schmidt, N-O, Mohan, S, Yong, WH, Seshagiri, S, Modrusan, Z, Jiang, Z, Aldape, KD, Mischel, PS, Liau, LM, Escovedo, CJ, Chen, W, Nghiemphu, PL, James, CD, Prados, MD, Westphal, M, Lamszus, K, Cloughesy, T & Phillips, HS 2011, 'Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.', J CLIN ONCOL, Jg. 29, Nr. 34, 34, S. 4482-4490. <http://www.ncbi.nlm.nih.gov/pubmed/22025148?dopt=Citation>

APA

Lai, A., Kharbanda, S., Pope, W. B., Tran, A., Solis, O. E., Peale, F., Forrest, W. F., Pujara, K., Carrillo, J. A., Pandita, A., Ellingson, B. M., Bowers, C. W., Soriano, R. H., Schmidt, N-O., Mohan, S., Yong, W. H., Seshagiri, S., Modrusan, Z., Jiang, Z., ... Phillips, H. S. (2011). Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. J CLIN ONCOL, 29(34), 4482-4490. [34]. http://www.ncbi.nlm.nih.gov/pubmed/22025148?dopt=Citation

Vancouver

Lai A, Kharbanda S, Pope WB, Tran A, Solis OE, Peale F et al. Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. J CLIN ONCOL. 2011;29(34):4482-4490. 34.

Bibtex

@article{db28ec747235435d84999c7428bc5c3f,
title = "Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.",
abstract = "Mutation in isocitrate dehydrogenase 1 (IDH1) at R132 (IDH1(R132MUT)) is frequent in low-grade diffuse gliomas and, within glioblastoma (GBM), has been proposed as a marker for GBMs that arise by transformation from lower-grade gliomas, regardless of clinical history. To determine how GBMs arising with IDH1(R132MUT) differ from other GBMs, we undertook a comprehensive comparison of patients presenting clinically with primary GBM as a function of IDH1(R132) mutation status.",
keywords = "Adult, Humans, Male, Aged, Female, Middle Aged, Aged, 80 and over, Mutation, Base Sequence, Brain Neoplasms/*genetics, *Cell Lineage, Cell Transformation, Neoplastic/genetics, *Evolution, Molecular, Genes, p53, Glioblastoma/*genetics, Glioma/genetics, Isocitrate Dehydrogenase/*genetics, Adult, Humans, Male, Aged, Female, Middle Aged, Aged, 80 and over, Mutation, Base Sequence, Brain Neoplasms/*genetics, *Cell Lineage, Cell Transformation, Neoplastic/genetics, *Evolution, Molecular, Genes, p53, Glioblastoma/*genetics, Glioma/genetics, Isocitrate Dehydrogenase/*genetics",
author = "Albert Lai and Samir Kharbanda and Pope, {Whitney B} and Anh Tran and Solis, {Orestes E} and Franklin Peale and Forrest, {William F} and Kanan Pujara and Carrillo, {Jose A} and Ajay Pandita and Ellingson, {Benjamin M} and Bowers, {Chauncey W} and Soriano, {Robert H} and Nils-Ole Schmidt and Sankar Mohan and Yong, {William H} and Somasekar Seshagiri and Zora Modrusan and Zhaoshi Jiang and Aldape, {Kenneth D} and Mischel, {Paul S} and Liau, {Linda M} and Escovedo, {Cameron J} and Weidong Chen and Nghiemphu, {Phioanh Leia} and James, {C David} and Prados, {Michael D} and Manfred Westphal and Katrin Lamszus and Timothy Cloughesy and Phillips, {Heidi S}",
year = "2011",
language = "English",
volume = "29",
pages = "4482--4490",
journal = "J CLIN ONCOL",
issn = "0732-183X",
publisher = "American Society of Clinical Oncology",
number = "34",

}

RIS

TY - JOUR

T1 - Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

AU - Lai, Albert

AU - Kharbanda, Samir

AU - Pope, Whitney B

AU - Tran, Anh

AU - Solis, Orestes E

AU - Peale, Franklin

AU - Forrest, William F

AU - Pujara, Kanan

AU - Carrillo, Jose A

AU - Pandita, Ajay

AU - Ellingson, Benjamin M

AU - Bowers, Chauncey W

AU - Soriano, Robert H

AU - Schmidt, Nils-Ole

AU - Mohan, Sankar

AU - Yong, William H

AU - Seshagiri, Somasekar

AU - Modrusan, Zora

AU - Jiang, Zhaoshi

AU - Aldape, Kenneth D

AU - Mischel, Paul S

AU - Liau, Linda M

AU - Escovedo, Cameron J

AU - Chen, Weidong

AU - Nghiemphu, Phioanh Leia

AU - James, C David

AU - Prados, Michael D

AU - Westphal, Manfred

AU - Lamszus, Katrin

AU - Cloughesy, Timothy

AU - Phillips, Heidi S

PY - 2011

Y1 - 2011

N2 - Mutation in isocitrate dehydrogenase 1 (IDH1) at R132 (IDH1(R132MUT)) is frequent in low-grade diffuse gliomas and, within glioblastoma (GBM), has been proposed as a marker for GBMs that arise by transformation from lower-grade gliomas, regardless of clinical history. To determine how GBMs arising with IDH1(R132MUT) differ from other GBMs, we undertook a comprehensive comparison of patients presenting clinically with primary GBM as a function of IDH1(R132) mutation status.

AB - Mutation in isocitrate dehydrogenase 1 (IDH1) at R132 (IDH1(R132MUT)) is frequent in low-grade diffuse gliomas and, within glioblastoma (GBM), has been proposed as a marker for GBMs that arise by transformation from lower-grade gliomas, regardless of clinical history. To determine how GBMs arising with IDH1(R132MUT) differ from other GBMs, we undertook a comprehensive comparison of patients presenting clinically with primary GBM as a function of IDH1(R132) mutation status.

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Mutation

KW - Base Sequence

KW - Brain Neoplasms/genetics

KW - Cell Lineage

KW - Cell Transformation, Neoplastic/genetics

KW - Evolution, Molecular

KW - Genes, p53

KW - Glioblastoma/genetics

KW - Glioma/genetics

KW - Isocitrate Dehydrogenase/genetics

KW - Adult

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Mutation

KW - Base Sequence

KW - Brain Neoplasms/genetics

KW - Cell Lineage

KW - Cell Transformation, Neoplastic/genetics

KW - Evolution, Molecular

KW - Genes, p53

KW - Glioblastoma/genetics

KW - Glioma/genetics

KW - Isocitrate Dehydrogenase/genetics

M3 - SCORING: Journal article

VL - 29

SP - 4482

EP - 4490

JO - J CLIN ONCOL

JF - J CLIN ONCOL

SN - 0732-183X

IS - 34

M1 - 34

ER -