Diffusion-weighted imaging in acute stroke--a tool of uncertain value?
Standard
Diffusion-weighted imaging in acute stroke--a tool of uncertain value? / Fiehler, Jens; Fiebach, Jochen B; Gass, Achim; Hoehn, Mathias; Kucinski, Thomas; Neumann-Haefelin, Tobias; Schellinger, Peter D; Siebler, Mario; Villringer, Arno; Röther, Joachim.
in: CEREBROVASC DIS, Jahrgang 14, Nr. 3-4, 3-4, 2002, S. 187-196.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Diffusion-weighted imaging in acute stroke--a tool of uncertain value?
AU - Fiehler, Jens
AU - Fiebach, Jochen B
AU - Gass, Achim
AU - Hoehn, Mathias
AU - Kucinski, Thomas
AU - Neumann-Haefelin, Tobias
AU - Schellinger, Peter D
AU - Siebler, Mario
AU - Villringer, Arno
AU - Röther, Joachim
PY - 2002
Y1 - 2002
N2 - The concept of a mismatch between the lesion volume in diffusion- and perfusion-weighted magnetic resonance imaging (MRI) indicating 'tissue at risk of infarction' is based on the assumption that tissue with diffusion slowing in diffusion-weighted MRI (DWI) or decreased values of the apparent diffusion coefficient represents irreversibly damaged tissue. Recent experimental as well as clinical studies, however, have shown that tissue with diffusion slowing may well normalize if the hypoperfusion is moderate or transient. We will interpret these findings in the light of experimental data and suggest a way for the interpretation of different time courses of lesion development in DWI within a clinical MRI protocol. MR stroke imaging delivers important information in acute stroke, particularly in defining the 'tissue at risk of infarction'.
AB - The concept of a mismatch between the lesion volume in diffusion- and perfusion-weighted magnetic resonance imaging (MRI) indicating 'tissue at risk of infarction' is based on the assumption that tissue with diffusion slowing in diffusion-weighted MRI (DWI) or decreased values of the apparent diffusion coefficient represents irreversibly damaged tissue. Recent experimental as well as clinical studies, however, have shown that tissue with diffusion slowing may well normalize if the hypoperfusion is moderate or transient. We will interpret these findings in the light of experimental data and suggest a way for the interpretation of different time courses of lesion development in DWI within a clinical MRI protocol. MR stroke imaging delivers important information in acute stroke, particularly in defining the 'tissue at risk of infarction'.
M3 - SCORING: Zeitschriftenaufsatz
VL - 14
SP - 187
EP - 196
JO - CEREBROVASC DIS
JF - CEREBROVASC DIS
SN - 1015-9770
IS - 3-4
M1 - 3-4
ER -