Aspirin-exacerbated respiratory disease: Update on medical management
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Aspirin-exacerbated respiratory disease: Update on medical management. / White, Andrew A; Woessner, Katharine; Simon, Ronald.
in: World journal of otorhinolaryngology - head and neck surgery, Jahrgang 6, Nr. 4, 12.2020, S. 241-247.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Aspirin-exacerbated respiratory disease: Update on medical management
AU - White, Andrew A
AU - Woessner, Katharine
AU - Simon, Ronald
N1 - © 2020 The Authors.
PY - 2020/12
Y1 - 2020/12
N2 - Aspirin-exacerbated respiratory disease (AERD) is frequently diagnosed in patients with severe type 2 airway inflammation presenting with nasal polyps and severe asthma. It has been associated with a recalcitrant course with high medical and surgical requirements. The advent of recent biological and other targeted treatments show promise in the medical management of patient with AERD. The goal of complete disease control where patients no longer require recurrent surgical procedures, systemic corticosteroid exposure and may live with a stable and relatively normal quality of life is now within reach. Further work is necessary to identify biomarkers predictive of treatment response.
AB - Aspirin-exacerbated respiratory disease (AERD) is frequently diagnosed in patients with severe type 2 airway inflammation presenting with nasal polyps and severe asthma. It has been associated with a recalcitrant course with high medical and surgical requirements. The advent of recent biological and other targeted treatments show promise in the medical management of patient with AERD. The goal of complete disease control where patients no longer require recurrent surgical procedures, systemic corticosteroid exposure and may live with a stable and relatively normal quality of life is now within reach. Further work is necessary to identify biomarkers predictive of treatment response.
U2 - 10.1016/j.wjorl.2020.07.009
DO - 10.1016/j.wjorl.2020.07.009
M3 - SCORING: Review article
C2 - 33336180
VL - 6
SP - 241
EP - 247
JO - World journal of otorhinolaryngology - head and neck surgery
JF - World journal of otorhinolaryngology - head and neck surgery
SN - 2095-8811
IS - 4
ER -