A novel membrane-permeant cADPR antagonist modified in the pyrophosphate bridge.
Beteiligte Einrichtungen
Abstract
A concise method for the formation of cyclopyrophosphate of cIDPRE as well as sulfur and selenium-substituted pyrophosphate cIDPRE analogues (P(1)(S)-cIDPRE, P(1)(Se)-cIDPRE, P(2)(S)-cIDPRE and P(2)(Se)-cIDPRE) was reported and one of the P(S)-diastereoisomers, P(1)(S)-cIDPRE-1, is a novel membrane-permeant cADPR antagonist.
Bibliografische Daten
| Originalsprache | Englisch |
|---|---|
| Aufsatznummer | 33 |
| ISSN | 1359-7345 |
| Status | Veröffentlicht - 2011 |
| pubmed | 21785757 |
|---|
