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A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19

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A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19. / Remppis, Jonathan; Ganzenmueller, Tina; Kohns Vasconcelos, Malte; Heinzel, Oliver; Handgretinger, Rupert; Renk, Hanna.

in: BMC INFECT DIS, Jahrgang 21, Nr. 1, 133, 01.02.2021.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Remppis, J, Ganzenmueller, T, Kohns Vasconcelos, M, Heinzel, O, Handgretinger, R & Renk, H 2021, 'A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19', BMC INFECT DIS, Jg. 21, Nr. 1, 133. https://doi.org/10.1186/s12879-021-05791-8

APA

Remppis, J., Ganzenmueller, T., Kohns Vasconcelos, M., Heinzel, O., Handgretinger, R., & Renk, H. (2021). A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19. BMC INFECT DIS, 21(1), [133]. https://doi.org/10.1186/s12879-021-05791-8

Vancouver

Remppis J, Ganzenmueller T, Kohns Vasconcelos M, Heinzel O, Handgretinger R, Renk H. A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19. BMC INFECT DIS. 2021 Feb 1;21(1). 133. https://doi.org/10.1186/s12879-021-05791-8

Bibtex

@article{bc44a1fc3f00401c805f9cdedd7bd314,
title = "A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19",
abstract = "BACKGROUND: While our knowledge about COVID-19 in adults has rapidly increased, data on the course of disease and outcome in children with different comorbidities is still limited.METHODS: Prospective, observational study at a tertiary care children's hospital in southern Germany. Clinical and virology data from all paediatric patients admitted with SARS-CoV-2 infection at our hospital were prospectively assessed.RESULTS: Between March and November 2020, 14 patients were admitted with COVID-19. One patient was admitted a second time with COVID-19 6 months after initial disease. Among seven patients with severe underlying comorbidities, three developed multisystem inflammatory syndrome (MIS-C), two were admitted to the paediatric intensive care unit. One patient needed invasive ventilation. Another patient died shortly after discharge of COVID-19-related complications.CONCLUSIONS: While COVID-19 generally causes mild disease in children, severe respiratory illness and MIS-C occur, in some cases with fatal outcome. Children with underlying diseases might be at special risk for severe disease.",
keywords = "Adolescent, COVID-19/diagnosis, Child, Child, Preschool, Comorbidity, Female, Germany, Hospitalization, Humans, Infant, Intensive Care Units, Pediatric, Male, Prospective Studies, SARS-CoV-2/isolation & purification, Systemic Inflammatory Response Syndrome/diagnosis, Tertiary Care Centers",
author = "Jonathan Remppis and Tina Ganzenmueller and {Kohns Vasconcelos}, Malte and Oliver Heinzel and Rupert Handgretinger and Hanna Renk",
year = "2021",
month = feb,
day = "1",
doi = "10.1186/s12879-021-05791-8",
language = "English",
volume = "21",
journal = "BMC INFECT DIS",
issn = "1471-2334",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19

AU - Remppis, Jonathan

AU - Ganzenmueller, Tina

AU - Kohns Vasconcelos, Malte

AU - Heinzel, Oliver

AU - Handgretinger, Rupert

AU - Renk, Hanna

PY - 2021/2/1

Y1 - 2021/2/1

N2 - BACKGROUND: While our knowledge about COVID-19 in adults has rapidly increased, data on the course of disease and outcome in children with different comorbidities is still limited.METHODS: Prospective, observational study at a tertiary care children's hospital in southern Germany. Clinical and virology data from all paediatric patients admitted with SARS-CoV-2 infection at our hospital were prospectively assessed.RESULTS: Between March and November 2020, 14 patients were admitted with COVID-19. One patient was admitted a second time with COVID-19 6 months after initial disease. Among seven patients with severe underlying comorbidities, three developed multisystem inflammatory syndrome (MIS-C), two were admitted to the paediatric intensive care unit. One patient needed invasive ventilation. Another patient died shortly after discharge of COVID-19-related complications.CONCLUSIONS: While COVID-19 generally causes mild disease in children, severe respiratory illness and MIS-C occur, in some cases with fatal outcome. Children with underlying diseases might be at special risk for severe disease.

AB - BACKGROUND: While our knowledge about COVID-19 in adults has rapidly increased, data on the course of disease and outcome in children with different comorbidities is still limited.METHODS: Prospective, observational study at a tertiary care children's hospital in southern Germany. Clinical and virology data from all paediatric patients admitted with SARS-CoV-2 infection at our hospital were prospectively assessed.RESULTS: Between March and November 2020, 14 patients were admitted with COVID-19. One patient was admitted a second time with COVID-19 6 months after initial disease. Among seven patients with severe underlying comorbidities, three developed multisystem inflammatory syndrome (MIS-C), two were admitted to the paediatric intensive care unit. One patient needed invasive ventilation. Another patient died shortly after discharge of COVID-19-related complications.CONCLUSIONS: While COVID-19 generally causes mild disease in children, severe respiratory illness and MIS-C occur, in some cases with fatal outcome. Children with underlying diseases might be at special risk for severe disease.

KW - Adolescent

KW - COVID-19/diagnosis

KW - Child

KW - Child, Preschool

KW - Comorbidity

KW - Female

KW - Germany

KW - Hospitalization

KW - Humans

KW - Infant

KW - Intensive Care Units, Pediatric

KW - Male

KW - Prospective Studies

KW - SARS-CoV-2/isolation & purification

KW - Systemic Inflammatory Response Syndrome/diagnosis

KW - Tertiary Care Centers

U2 - 10.1186/s12879-021-05791-8

DO - 10.1186/s12879-021-05791-8

M3 - SCORING: Journal article

C2 - 33522901

VL - 21

JO - BMC INFECT DIS

JF - BMC INFECT DIS

SN - 1471-2334

IS - 1

M1 - 133

ER -