A bioinformatic assay for pluripotency in human cells.
Standard
A bioinformatic assay for pluripotency in human cells. / Müller, Franz-Josef; Schuldt, Bernhard M; Williams, Roy; Mason, Dylan; Altun, Gulsah; Papapetrou, Eirini P; Danner, Sandra; Goldmann, Johanna E; Herbst, Arne; Schmidt, Nils-Ole; Aldenhoff, Josef B; Laurent, Louise C; Loring, Jeanne F.
in: NAT METHODS, Jahrgang 8, Nr. 4, 4, 2011, S. 315-354.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - A bioinformatic assay for pluripotency in human cells.
AU - Müller, Franz-Josef
AU - Schuldt, Bernhard M
AU - Williams, Roy
AU - Mason, Dylan
AU - Altun, Gulsah
AU - Papapetrou, Eirini P
AU - Danner, Sandra
AU - Goldmann, Johanna E
AU - Herbst, Arne
AU - Schmidt, Nils-Ole
AU - Aldenhoff, Josef B
AU - Laurent, Louise C
AU - Loring, Jeanne F
PY - 2011
Y1 - 2011
N2 - Pluripotent stem cells (PSCs) are defined by their potential to generate all cell types of an organism. The standard assay for pluripotency of mouse PSCs is cell transmission through the germline, but for human PSCs researchers depend on indirect methods such as differentiation into teratomas in immunodeficient mice. Here we report PluriTest, a robust open-access bioinformatic assay of pluripotency in human cells based on their gene expression profiles.
AB - Pluripotent stem cells (PSCs) are defined by their potential to generate all cell types of an organism. The standard assay for pluripotency of mouse PSCs is cell transmission through the germline, but for human PSCs researchers depend on indirect methods such as differentiation into teratomas in immunodeficient mice. Here we report PluriTest, a robust open-access bioinformatic assay of pluripotency in human cells based on their gene expression profiles.
M3 - SCORING: Zeitschriftenaufsatz
VL - 8
SP - 315
EP - 354
JO - NAT METHODS
JF - NAT METHODS
SN - 1548-7091
IS - 4
M1 - 4
ER -