(68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer

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(68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer : Abdom Imaging. / Eiber, M.; Nekolla, S. G.; Maurer, T.; Weirich, G.; Wester, H. J.; Schwaiger, M.

in: ABDOM IMAGING, Jahrgang 40, Nr. 6, 2015, S. 1769-1771.

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@article{d13d6f56129342259734fc0ca6284d6f,
title = "(68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer: Abdom Imaging",
abstract = "Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a (68)Gallium-labeled ligand of the prostate-specific membrane antigen ((68)Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68 Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric (68)Ga-PSMA PET/MR by combining molecular and structural information.",
keywords = "Aged Antigens, Surface Edetic Acid/*analogs & derivatives *Gallium Radioisotopes Glutamate Carboxypeptidase II Humans Magnetic Resonance Imaging Male Multimodal Imaging Neoplasm Staging/methods *Oligopeptides Positron-Emission Tomography Preoperative Care Prostatic Neoplasms/*diagnosis/diagnostic imaging/surgery",
author = "M. Eiber and Nekolla, {S. G.} and T. Maurer and G. Weirich and Wester, {H. J.} and M. Schwaiger",
note = "1432-0509 Eiber, Matthias Nekolla, Stephan G Maurer, Tobias Weirich, Gregor Wester, Hans-Jurgen Schwaiger, Markus Case Reports Journal Article United States Abdom Imaging. 2015 Aug;40(6):1769-71. doi: 10.1007/s00261-014-0301-z.",
year = "2015",
doi = "10.1007/s00261-014-0301-z",
language = "English",
volume = "40",
pages = "1769--1771",
journal = "ABDOM IMAGING",
issn = "0942-8925",
publisher = "Springer New York",
number = "6",

}

RIS

TY - JOUR

T1 - (68)Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer

T2 - Abdom Imaging

AU - Eiber, M.

AU - Nekolla, S. G.

AU - Maurer, T.

AU - Weirich, G.

AU - Wester, H. J.

AU - Schwaiger, M.

N1 - 1432-0509 Eiber, Matthias Nekolla, Stephan G Maurer, Tobias Weirich, Gregor Wester, Hans-Jurgen Schwaiger, Markus Case Reports Journal Article United States Abdom Imaging. 2015 Aug;40(6):1769-71. doi: 10.1007/s00261-014-0301-z.

PY - 2015

Y1 - 2015

N2 - Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a (68)Gallium-labeled ligand of the prostate-specific membrane antigen ((68)Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68 Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric (68)Ga-PSMA PET/MR by combining molecular and structural information.

AB - Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a (68)Gallium-labeled ligand of the prostate-specific membrane antigen ((68)Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68 Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric (68)Ga-PSMA PET/MR by combining molecular and structural information.

KW - Aged Antigens, Surface Edetic Acid/analogs & derivatives Gallium Radioisotopes Glutamate Carboxypeptidase II Humans Magnetic Resonance Imaging Male Multimodal Imaging Neoplasm Staging/methods Oligopeptides Positron-Emission Tomography Preoperative Care Pr

U2 - 10.1007/s00261-014-0301-z

DO - 10.1007/s00261-014-0301-z

M3 - SCORING: Journal article

VL - 40

SP - 1769

EP - 1771

JO - ABDOM IMAGING

JF - ABDOM IMAGING

SN - 0942-8925

IS - 6

ER -